Anti-Aging Strategies to Prevent Diseases: Promoting Longevity and Optimal Health
Keywords:
Anti-Aging Strategies , Prevention, Longevity , Optimal HealthAbstract
Anti-aging strategies extend beyond cosmetic concerns, reaching into the realm of disease prevention, promoting longevity, and optimizing overall health. The quest for a longer, healthier life involves a multifaceted approach that intertwines scientific advancements, lifestyle modifications, and holistic well-being. At the forefront of anti-aging strategies is the understanding of cellular processes and their impact on aging. Scientific breakthroughs explore genetic interventions, cellular repair mechanisms, and the role of inflammation in aging-related diseases. Targeting these processes offers the potential to delay or mitigate the onset of various health conditions, fostering longevity. Lifestyle modifications form a pivotal element in anti-aging endeavors. Healthy nutrition, regular exercise, and stress management play instrumental roles in disease prevention. A balanced diet rich in antioxidants and essential nutrients supports cellular health, while physical activity maintains cardiovascular fitness and reduces the risk of chronic illnesses. Holistic well-being, encompassing mental health and social connections, is integral to anti-aging strategies. Chronic stress and social isolation contribute to accelerated aging, emphasizing the importance of mental and emotional wellness. Practices like meditation, adequate sleep, and strong social networks become essential components in the pursuit of optimal health and longevity. In summary, anti-aging strategies with a focus on disease prevention embrace a holistic paradigm. By intertwining scientific advancements, lifestyle modifications, and holistic well-being, individuals can embark on a journey towards not only extending their lifespan but also enhancing the quality of their years. This comprehensive approach to anti-aging reflects a commitment to promoting longevity and optimal health across the lifespan.
References
Achem SR, Devault KR. Dysphagia in aging. J Clin Gastroenterol. 2005;39(5):357-71.
Ager CL, White LW, Mayberry WL, Crist PA, Conrad ME. Creative aging. Int J Aging Hum Dev. 1981;14(1):67-76.
Aguilar-Hernández L, Alejandre R, César Morales-Medina J, Iannitti T, Flores G. Cellular mechanisms in brain aging: Focus on physiological and pathological aging. J Chem Neuroanat. 2023;128:102210.
Amenta F, Zaccheo D, Collier WL. Neurotransmitters, neuroreceptors and aging. Mech Ageing Dev. 1991;61(3):249-73.
Anderson R, Prolla T. PGC-1alpha in aging and anti-aging interventions. Biochim Biophys Acta. 2009;1790(10):1059-66.
Antignano I, Liu Y, Offermann N, Capasso M. Aging microglia. Cell Mol Life Sci. 2023;80(5):126.
Arai Y, Takayama M, Abe Y, Hirose N. Adipokines and aging. J Atheroscler Thromb. 2011;18(7):545-50.
Aubert G, Lansdorp PM. Telomeres and aging. Physiol Rev. 2008;88(2):557-79.
Austad SN. Is aging programed? Aging Cell. 2004;3(5):249-51.
Bai X. Biomarkers of Aging. Adv Exp Med Biol. 2018;1086:217-34.
Bakthavatchalu V, Muthupalani S, Marini RP, Fox JG. Endocrinopathy and Aging in Ferrets. Vet Pathol. 2016;53(2):349-65.
Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell. 2005;120(4):483-95.
Bana B, Cabreiro F. The Microbiome and Aging. Annu Rev Genet. 2019;53:239-61.
Bance M. Hearing and aging. Cmaj. 2007;176(7):925-7.
Bao H, Cao J, Chen M, Chen M, Chen W, Chen X, et al. Biomarkers of aging. Sci China Life Sci. 2023;66(5):893-1066.
Barbagallo M, Dominguez LJ. Magnesium and aging. Curr Pharm Des. 2010;16(7):832-9.
Barcelos IP, Haas RH. CoQ10 and Aging. Biology (Basel). 2019;8(2).
Bartels MN, Omura A. Aging in polio. Phys Med Rehabil Clin N Am. 2005;16(1):197-218.
Bartke A. Insulin and aging. Cell Cycle. 2008;7(21):3338-43.
Behfar Q, Ramirez Zuniga A, Martino-Adami PV. Aging, Senescence, and Dementia. J Prev Alzheimers Dis. 2022;9(3):523-31.
Ben-Avraham D. Epigenetics of aging. Adv Exp Med Biol. 2015;847:179-91.
Bergler-Czop B, Miziołek B. Aging - What Do We Know? Acta Dermatovenerol Croat. 2017;25(1):50-6.
Bischoff SC. Microbiota and aging. Curr Opin Clin Nutr Metab Care. 2016;19(1):26-30.
Blagosklonny MV. Paradoxes of aging. Cell Cycle. 2007;6(24):2997-3003.
Blagosklonny MV. Aging: ROS or TOR. Cell Cycle. 2008;7(21):3344-54.
Bolognia JL. Aging skin. Am J Med. 1995;98(1a):99s-103s.
Bondy SC. Melatonin and Aging. Subcell Biochem. 2023;103:291-307.
Booth LN, Brunet A. The Aging Epigenome. Mol Cell. 2016;62(5):728-44.
Bosch JV. Filming "successful aging". Gerontologist. 2015;55(1):169-70.
Bouleftour W, Magne N. Aging preclinical models in oncology field: from cells to aging. Aging Clin Exp Res. 2022;34(4):751-5.
Bowden DM, Williams DD. Aging. Adv Vet Sci Comp Med. 1984;28:305-41.
Brandes RP, Fleming I, Busse R. Endothelial aging. Cardiovasc Res. 2005;66(2):286-94.
Brisset M, Nicolas G. Peripheral neuropathies and aging. Geriatr Psychol Neuropsychiatr Vieil. 2018;16(4):409-13.
Brock MA. Chronobiology and aging. J Am Geriatr Soc. 1991;39(1):74-91.
Brunet A, Berger SL. Epigenetics of aging and aging-related disease. J Gerontol A Biol Sci Med Sci. 2014;69 Suppl 1(Suppl 1):S17-20.
Buford TW. Hypertension and aging. Ageing Res Rev. 2016;26:96-111.
Bustacchini S, Corsonello A, Onder G, Guffanti EE, Marchegiani F, Abbatecola AM, et al. Pharmacoeconomics and aging. Drugs Aging. 2009;26 Suppl 1:75-87.
Cai Y, Song W, Li J, Jing Y, Liang C, Zhang L, et al. The landscape of aging. Sci China Life Sci. 2022;65(12):2354-454.
Cai Z, Zhang J, Li H. Selenium, aging and aging-related diseases. Aging Clin Exp Res. 2019;31(8):1035-47.
Campbell S. Will Biotechnology Stop Aging? IEEE Pulse. 2019;10(2):3-7.
Cannon ML. What is aging? Dis Mon. 2015;61(11):454-9.
Cao W. IFN-Aging: Coupling Aging With Interferon Response. Front Aging. 2022;3:870489.
Carmeli E, Patish H, Coleman R. The aging hand. J Gerontol A Biol Sci Med Sci. 2003;58(2):146-52.
Catapano M, Ahmed M, Breslow RG, Borg-Stein J. The aging athlete. Pm r. 2022;14(5):643-51.
Chapman IM. Obesity paradox during aging. Interdiscip Top Gerontol. 2010;37:20-36.
Chebly A, Khalil C, Kuzyk A, Beylot-Barry M, Chevret E. T-cell lymphocytes' aging clock: telomeres, telomerase and aging. Biogerontology. 2023.
Chia CW, Yeager SM, Egan JM. Endocrinology of Taste with Aging. Endocrinol Metab Clin North Am. 2023;52(2):295-315.
Chiao YA, Rabinovitch PS. The Aging Heart. Cold Spring Harb Perspect Med. 2015;5(9):a025148.
Cho I. Aging blepharoplasty. Arch Plast Surg. 2013;40(5):486-91.
Cohen RA, Marsiske MM, Smith GE. Neuropsychology of aging. Handb Clin Neurol. 2019;167:149-80.
Cook JM, Simiola V. Trauma and Aging. Curr Psychiatry Rep. 2018;20(10):93.
Cooper LT, Cooke JP, Dzau VJ. The vasculopathy of aging. J Gerontol. 1994;49(5):B191-6.
Córdova-Oriz I, Chico-Sordo L, Varela E. Telomeres, aging and reproduction. Curr Opin Obstet Gynecol. 2022;34(3):151-8.
Courtney-Martin G, Ball RO, Pencharz PB, Elango R. Protein Requirements during Aging. Nutrients. 2016;8(8).
Cutler RG. Antioxidants and aging. Am J Clin Nutr. 1991;53(1 Suppl):373s-9s.
Cutler RG, Mattson MP. The adversities of aging. Ageing Res Rev. 2006;5(3):221-38.
D'Aquila P, Rose G, Bellizzi D, Passarino G. Epigenetics and aging. Maturitas. 2013;74(2):130-6.
Dai W, Wang X. Aging in check. Sci Aging Knowledge Environ. 2006;2006(7):pe9.
Dall'Olio F. Glycobiology of Aging. Subcell Biochem. 2018;90:505-26.
Dhar HL. Physiology of aging. Indian J Med Sci. 1998;52(11):485-97.
Di Francesco V, Fantin F, Omizzolo F, Residori L, Bissoli L, Bosello O, et al. The anorexia of aging. Dig Dis. 2007;25(2):129-37.
Diamanti-Kandarakis E, Dattilo M, Macut D, Duntas L, Gonos ES, Goulis DG, et al. MECHANISMS IN ENDOCRINOLOGY: Aging and anti-aging: a Combo-Endocrinology overview. Eur J Endocrinol. 2017;176(6):R283-r308.
Duffy JF, Zitting KM, Chinoy ED. Aging and Circadian Rhythms. Sleep Med Clin. 2015;10(4):423-34.
Echeverri Tirado LC, Ferrer JE, Herrera AM. Aging and Erectile Dysfunction. Sex Med Rev. 2016;4(1):63-73.
Edo MD, Andrés V. Aging, telomeres, and atherosclerosis. Cardiovasc Res. 2005;66(2):213-21.
Ehninger D, Neff F, Xie K. Longevity, aging and rapamycin. Cell Mol Life Sci. 2014;71(22):4325-46.
Ellison D, White D, Farrar FC. Aging population. Nurs Clin North Am. 2015;50(1):185-213.
Epel E. How "reversible" is telomeric aging? Cancer Prev Res (Phila). 2012;5(10):1163-8.
Everitt A, Meites J. Aging and anti-aging effects of hormones. J Gerontol. 1989;44(6):B139-47.
Fang W, Chen S, Jin X, Liu S, Cao X, Liu B. Metabolomics in aging research: aging markers from organs. Front Cell Dev Biol. 2023;11:1198794.
Fedok FG. The aging face. Facial Plast Surg. 1996;12(2):107-15.
Fenske NA, Conard CB. Aging skin. Am Fam Physician. 1988;37(2):219-30.
Fitzgerald R, Graivier MH, Kane M, Lorenc ZP, Vleggaar D, Werschler WP, et al. Update on facial aging. Aesthet Surg J. 2010;30 Suppl:11s-24s.
Flaherty JH, Morley JE. Anti-aging. Clin Geriatr Med. 2004;20(2):xi-xv.
Franceschi C, Garagnani P, Vitale G, Capri M, Salvioli S. Inflammaging and 'Garb-aging'. Trends Endocrinol Metab. 2017;28(3):199-212.
Franchini M. Hemostasis and aging. Crit Rev Oncol Hematol. 2006;60(2):144-51.
Frangos E, Graf C, Samaras N. Functional Aging: Integrating Functionality to a Multidimensional Assessment of Healthy Aging. Curr Gerontol Geriatr Res. 2023;2023:9409918.
Freije JM, López-Otín C. Reprogramming aging and progeria. Curr Opin Cell Biol. 2012;24(6):757-64.
Frolkis VV. Syndromes of aging. Gerontology. 1992;38(1-2):80-6.
Fukutomi M, Kario K. Aging and hypertension. Expert Rev Cardiovasc Ther. 2010;8(11):1531-9.
Fung HH. Aging in culture. Gerontologist. 2013;53(3):369-77.
Gadaleta MN, Cormio A, Pesce V, Lezza AM, Cantatore P. Aging and mitochondria. Biochimie. 1998;80(10):863-70.
Galkin F, Zhang B, Dmitriev SE, Gladyshev VN. Reversibility of irreversible aging. Ageing Res Rev. 2019;49:104-14.
Galluzzi S, Beltramello A, Filippi M, Frisoni GB. Aging. Neurol Sci. 2008;29 Suppl 3:296-300.
Ginsberg TB. Aging and sexuality. Med Clin North Am. 2006;90(5):1025-36.
Glück J. Wisdom and aging. Curr Opin Psychol. 2023;55:101742.
Goltzman D. The Aging Skeleton. Adv Exp Med Biol. 2019;1164:153-60.
Goronzy JJ, Weyand CM. Immune aging and autoimmunity. Cell Mol Life Sci. 2012;69(10):1615-23.
Gries KJ, Trappe SW. The Aging Athlete: Paradigm of Healthy Aging. Int J Sports Med. 2022;43(8):661-78.
Groarke EM, Young NS. Aging and Hematopoiesis. Clin Geriatr Med. 2019;35(3):285-93.
Guaraldi G, Milic J, Mussini C. Aging with HIV. Curr HIV/AIDS Rep. 2019;16(6):475-81.
Guedes G, Tsai JC, Loewen NA. Glaucoma and aging. Curr Aging Sci. 2011;4(2):110-7.
Guest PC. Metabolic Biomarkers in Aging and Anti-Aging Research. Adv Exp Med Biol. 2019;1178:247-64.
Guyuron B. The aging nose. Dermatol Clin. 1997;15(4):659-64.
Hamet P, Tremblay J. Genes of aging. Metabolism. 2003;52(10 Suppl 2):5-9.
Harman D. Aging: overview. Ann N Y Acad Sci. 2001;928:1-21.
Hassett AL, Clauw DJ, Williams DA. Premature Aging in Fibromyalgia. Curr Aging Sci. 2015;8(2):178-85.
Hayflick L. Aging under glass. Exp Gerontol. 1970;5(4):291-303.
He Y, Jasper H. Studying aging in Drosophila. Methods. 2014;68(1):129-33.
Hemmatian H, Bakker AD, Klein-Nulend J, van Lenthe GH. Aging, Osteocytes, and Mechanotransduction. Curr Osteoporos Rep. 2017;15(5):401-11.
Holland J, Greenstein M. Changing how we view aging. J Geriatr Oncol. 2015;6(3):175-7.
Hur JH, Cho J, Walker DW. Aging: Dial M for Mitochondria. Aging (Albany NY). 2010;2(1):69-73.
Isaev NK, Genrikhs EE, Oborina MV, Stelmashook EV. Accelerated aging and aging process in the brain. Rev Neurosci. 2018;29(3):233-40.
Jahangir A, Sagar S, Terzic A. Aging and cardioprotection. J Appl Physiol (1985). 2007;103(6):2120-8.
Janssens GE, Veenhoff LM. Evidence for the hallmarks of human aging in replicatively aging yeast. Microb Cell. 2016;3(7):263-74.
Jasim S, Gharib H. THYROID AND AGING. Endocr Pract. 2018;24(4):369-74.
Jenkins HA, Furman JM, Gulya AJ, Honrubia V, Linthicum FH, Mirka A. Dysequilibrium of aging. Otolaryngol Head Neck Surg. 1989;100(4):272-82.
Jin J, Wang GL, Timchenko L, Timchenko NA. GSK3beta and aging liver. Aging (Albany NY). 2009;1(6):582-5.
Jin L, Song Q, Zhang W, Geng B, Cai J. Roles of long noncoding RNAs in aging and aging complications. Biochim Biophys Acta Mol Basis Dis. 2019;1865(7):1763-71.
Kaeberlein M, Kennedy BK, Liu X, Suh Y, Zhou Z. Trinations aging symposium. Mech Ageing Dev. 2011;132(6-7):348-52.
Kamel HK. Sarcopenia and aging. Nutr Rev. 2003;61(5 Pt 1):157-67.
Kanasi E, Ayilavarapu S, Jones J. The aging population: demographics and the biology of aging. Periodontol 2000. 2016;72(1):13-8.
Karasek M, Reiter RJ. Melatonin and aging. Neuro Endocrinol Lett. 2002;23 Suppl 1:14-6.
Katlic MR, Coleman J. The Aging Surgeon. Adv Surg. 2016;50(1):93-103.
Katz JD. The aging anesthesiologist. Curr Opin Anaesthesiol. 2016;29(2):206-11.
Kaushik S, Cuervo AM. Proteostasis and aging. Nat Med. 2015;21(12):1406-15.
Khaw KT. Healthy aging. Bmj. 1997;315(7115):1090-6.
Klausner SC, Schwartz AB. The aging heart. Clin Geriatr Med. 1985;1(1):119-41.
Kmieć Z, Pétervári E, Balaskó M, Székely M. Anorexia of aging. Vitam Horm. 2013;92:319-55.
Knight JA. The biochemistry of aging. Adv Clin Chem. 2000;35:1-62.
Ko AC, Korn BS, Kikkawa DO. The aging face. Surv Ophthalmol. 2017;62(2):190-202.
Konrad HR, Girardi M, Helfert R. Balance and aging. Laryngoscope. 1999;109(9):1454-60.
Kotloski RJ, Dowding J, Hermann BP, Sutula TP. Epilepsy and aging. Handb Clin Neurol. 2019;167:455-75.
Kudlow BA, Kennedy BK. Aging: progeria and the lamin connection. Curr Biol. 2006;16(16):R652-4.
Kumar S, Peterson TR. Moonshots for aging. Nutr Healthy Aging. 2020;5(4):239-46.
Kuro-o M. Klotho and aging. Biochim Biophys Acta. 2009;1790(10):1049-58.
la Torre A, Lo Vecchio F, Greco A. Epigenetic Mechanisms of Aging and Aging-Associated Diseases. Cells. 2023;12(8).
Lakatta EG. So! What's aging? Is cardiovascular aging a disease? J Mol Cell Cardiol. 2015;83:1-13.
Lamberts SW, van den Beld AW, van der Lely AJ. The endocrinology of aging. Science. 1997;278(5337):419-24.
Lamster IB, Asadourian L, Del Carmen T, Friedman PK. The aging mouth: differentiating normal aging from disease. Periodontol 2000. 2016;72(1):96-107.
Lee HC, Wei YH. Mitochondria and aging. Adv Exp Med Biol. 2012;942:311-27.
Lester AW, Moffat SD, Wiener JM, Barnes CA, Wolbers T. The Aging Navigational System. Neuron. 2017;95(5):1019-35.
Leveille SG. Musculoskeletal aging. Curr Opin Rheumatol. 2004;16(2):114-8.
Li L, Wang Z. Ovarian Aging and Osteoporosis. Adv Exp Med Biol. 2018;1086:199-215.
Li YS, Xiao WF, Luo W. Cellular aging towards osteoarthritis. Mech Ageing Dev. 2017;162:80-4.
Li Z, Wang Z. Aging Kidney and Aging-Related Disease. Adv Exp Med Biol. 2018;1086:169-87.
Liao S, Ning Q, Chen Y, Zhao X, Tang S. Interaction of aging and Immunosenescence: New therapeutic targets of aging. Int Immunopharmacol. 2022;113(Pt A):109397.
Lin YY, Huang CS. Aging in Taiwan: Building a Society for Active Aging and Aging in Place. Gerontologist. 2016;56(2):176-83.
Litvak J, Maggi S. Aging. Infect Dis Clin North Am. 1991;5(2):353-63.
Loeser RF. Aging and osteoarthritis. Curr Opin Rheumatol. 2011;23(5):492-6.
Lord SR, Delbaere K, Sturnieks DL. Aging. Handb Clin Neurol. 2018;159:157-71.
Lowery EM, Brubaker AL, Kuhlmann E, Kovacs EJ. The aging lung. Clin Interv Aging. 2013;8:1489-96.
Lu M, Wang Z. Microbiota and Aging. Adv Exp Med Biol. 2018;1086:141-56.
Luo L, Qin ZH. Autophagy, Aging, and Longevity. Adv Exp Med Biol. 2019;1206:509-25.
Luo XY, Qu SL, Tang ZH, Zhang Y, Liu MH, Peng J, et al. SIRT1 in cardiovascular aging. Clin Chim Acta. 2014;437:106-14.
Madden CL, Cloyes KG. The discourse of aging. ANS Adv Nurs Sci. 2012;35(3):264-72.
Malandrino N, Bhat SZ, Alfaraidhy M, Grewal RS, Kalyani RR. Obesity and Aging. Endocrinol Metab Clin North Am. 2023;52(2):317-39.
Mammen JSR. Thyroid and Aging. Endocrinol Metab Clin North Am. 2023;52(2):229-43.
Mao CC, Cai X. Nanomaterials and Aging. Curr Stem Cell Res Ther. 2021;16(1):57-65.
Mariotti S, Franceschi C, Cossarizza A, Pinchera A. The aging thyroid. Endocr Rev. 1995;16(6):686-715.
Maroulis GB. Ovarian aging. Ann N Y Acad Sci. 1997;816:22-6.
Martin LG. The aging of Asia. J Gerontol. 1988;43(4):S99-113.
Martinez-Lopez N, Athonvarangkul D, Singh R. Autophagy and aging. Adv Exp Med Biol. 2015;847:73-87.
Martins RH, Gonçalvez TM, Pessin AB, Branco A. Aging voice: presbyphonia. Aging Clin Exp Res. 2014;26(1):1-5.
Masoro EJ. Physiology of aging. Int J Sport Nutr Exerc Metab. 2001;11 Suppl:S218-22.
Maxwell PH. What might retrotransposons teach us about aging? Curr Genet. 2016;62(2):277-82.
McCann H, Durand B, Shepherd CE. Aging-Related Tau Astrogliopathy in Aging and Neurodegeneration. Brain Sci. 2021;11(7).
McMahon M, Forester C, Buffenstein R. Aging through an epitranscriptomic lens. Nat Aging. 2021;1(4):335-46.
Mendelsohn AR, Larrick JW. Rejuvenation of aging hearts. Rejuvenation Res. 2013;16(4):330-2.
Meston CM. Aging and sexuality. West J Med. 1997;167(4):285-90.
Meyer KC. Aging. Proc Am Thorac Soc. 2005;2(5):433-9.
Miles LE, Dement WC. Sleep and aging. Sleep. 1980;3(2):1-220.
Miller RA. Genes against aging. J Gerontol A Biol Sci Med Sci. 2012;67(5):495-502.
Miquel PA. Aging as alteration. Interdiscip Top Gerontol. 2014;39:187-97.
Mitteldorf J. Can Aging be Programmed? Biochemistry (Mosc). 2018;83(12):1524-33.
Mooradian AD, Morley JE, Korenman SG. Endocrinology in aging. Dis Mon. 1988;34(7):393-461.
Morley JE, Thomas DR. Anorexia and aging: pathophysiology. Nutrition. 1999;15(6):499-503.
Mouthon L. [Immunity, autoimmunity, aging]. Rev Med Interne. 2008;29 Suppl 3:S277-80.
Musso CG, Giordani MC, Imperiali N. Aging Kidney Transplantation. Rev Invest Clin. 2016;68(2):68-74.
Nagami P, Yoshikawa TT. Aging and tuberculosis. Gerontology. 1984;30(5):308-15.
Nair KS. Aging muscle. Am J Clin Nutr. 2005;81(5):953-63.
Nakanishi K, Daimon M. Aging and myocardial strain. J Med Ultrason (2001). 2022;49(1):53-60.
Newmann JP. Aging and depression. Psychol Aging. 1989;4(2):150-65.
Nicosia SV. The aging ovary. Med Clin North Am. 1987;71(1):1-9.
Norman DC, Grahn D, Yoshikawa TT. Fever and aging. J Am Geriatr Soc. 1985;33(12):859-63.
Oakley R, Tharakan B. Vascular hyperpermeability and aging. Aging Dis. 2014;5(2):114-25.
Obas V, Vasan RS. The aging heart. Clin Sci (Lond). 2018;132(13):1367-82.
Owsley C. Aging and vision. Vision Res. 2011;51(13):1610-22.
Owsley C. Vision and Aging. Annu Rev Vis Sci. 2016;2:255-71.
Oxman TE. Reflections on Tribalism and Aging. Am J Geriatr Psychiatry. 2021;29(12):1290-5.
Ozawa Y, Kubota S, Narimatsu T, Yuki K, Koto T, Sasaki M, et al. Retinal aging and sirtuins. Ophthalmic Res. 2010;44(3):199-203.
Pal S, Tyler JK. Epigenetics and aging. Sci Adv. 2016;2(7):e1600584.
Palmer AL, Ousman SS. Astrocytes and Aging. Front Aging Neurosci. 2018;10:337.
Pamplona R, Jové M, Gómez J, Barja G. Whole organism aging: Parabiosis, inflammaging, epigenetics, and peripheral and central aging clocks. The ARS of aging. Exp Gerontol. 2023;174:112137.
Park DC, Yeo SG. Aging. Korean J Audiol. 2013;17(2):39-44.
Parmalee NL, Aschner M. Manganese and aging. Neurotoxicology. 2016;56:262-8.
Peppa M, Uribarri J, Vlassara H. Aging and glycoxidant stress. Hormones (Athens). 2008;7(2):123-32.
Pérez V, Sierra F. [Biology of aging]. Rev Med Chil. 2009;137(2):296-302.
Persson PB. Aging. Am J Physiol Regul Integr Comp Physiol. 2002;282(1):R1-2.
Petr MA, Tulika T, Carmona-Marin LM, Scheibye-Knudsen M. Protecting the Aging Genome. Trends Cell Biol. 2020;30(2):117-32.
Phillip JM, Aifuwa I, Walston J, Wirtz D. The Mechanobiology of Aging. Annu Rev Biomed Eng. 2015;17:113-41.
Philpot CD. Paraphilia and aging. Clin Geriatr Med. 2003;19(3):629-36, viii-ix.
Pi Y, Goldenthal MJ, Marín-García J. Mitochondrial channelopathies in aging. J Mol Med (Berl). 2007;85(9):937-51.
Piper MD, Bartke A. Diet and aging. Cell Metab. 2008;8(2):99-104.
Puizina-Ivić N. Skin aging. Acta Dermatovenerol Alp Pannonica Adriat. 2008;17(2):47-54.
Queen BL, Tollefsbol TO. Polyphenols and aging. Curr Aging Sci. 2010;3(1):34-42.
Rando TA, Chang HY. Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell. 2012;148(1-2):46-57.
Rattan SI. Aging, anti-aging, and hormesis. Mech Ageing Dev. 2004;125(4):285-9.
Rattan SI. Hormesis in aging. Ageing Res Rev. 2008;7(1):63-78.
Razgonova MP, Zakharenko AM, Golokhvast KS, Thanasoula M, Sarandi E, Nikolouzakis K, et al. Telomerase and telomeres in aging theory and chronographic aging theory (Review). Mol Med Rep. 2020;22(3):1679-94.
Reynolds JC, Bwiza CP, Lee C. Mitonuclear genomics and aging. Hum Genet. 2020;139(3):381-99.
Ribarič S. Diet and aging. Oxid Med Cell Longev. 2012;2012:741468.
Riera CE. Frontiers in Neuroscience
ThermoTRPs: Role in Aging. In: Emir TLR, editor. Neurobiology of TRP Channels. Boca Raton (FL): CRC Press/Taylor & Francis
© 2018 by Taylor & Francis Group, LLC.; 2017. p. 265-75.
Riera CE, Dillin A. Can aging be 'drugged'? Nat Med. 2015;21(12):1400-5.
Rocha A, Magalhães S, Nunes A. Study Aging by Fibroblasts Metabolome. Curr Mol Med. 2021;21(4):300-17.
Rowe JW, Kahn RL. Successful aging. Gerontologist. 1997;37(4):433-40.
Ruan Q, Ma C, Zhang R, Yu Z. Current status of auditory aging and anti-aging research. Geriatr Gerontol Int. 2014;14(1):40-53.
Rubinsztein DC, Mariño G, Kroemer G. Autophagy and aging. Cell. 2011;146(5):682-95.
Samuels MH. Hyperthyroidism in Aging. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, et al., editors. Endotext. South Dartmouth (MA): MDText.com, Inc.
Copyright © 2000-2024, MDText.com, Inc.; 2000.
Santhanam L, Christianson DW, Nyhan D, Berkowitz DE. Arginase and vascular aging. J Appl Physiol (1985). 2008;105(5):1632-42.
Saul D, Kosinsky RL. Epigenetics of Aging and Aging-Associated Diseases. Int J Mol Sci. 2021;22(1).
Scheibye-Knudsen M. Neurodegeneration in accelerated aging. Dan Med J. 2016;63(11).
Sfeir JG, Drake MT, Khosla S, Farr JN. Skeletal Aging. Mayo Clin Proc. 2022;97(6):1194-208.
Shah AR, Kennedy PM. The Aging Face. Med Clin North Am. 2018;102(6):1041-54.
Shay JW. Telomeres and aging. Curr Opin Cell Biol. 2018;52:1-7.
Sheehan MN. Disabilities and aging. Theor Med Bioeth. 2003;24(6):525-33.
Shen LR, Parnell LD, Ordovas JM, Lai CQ. Curcumin and aging. Biofactors. 2013;39(1):133-40.
Sherrard DJ. Renal osteodystrophy and aging. Semin Nephrol. 2009;29(6):636-42.
Shifren JL, Schiff I. The aging ovary. J Womens Health Gend Based Med. 2000;9 Suppl 1:S3-7.
Shin SH, Lee YH, Rho NK, Park KY. Skin aging from mechanisms to interventions: focusing on dermal aging. Front Physiol. 2023;14:1195272.
Shukitt-Hale B. Blueberries and neuronal aging. Gerontology. 2012;58(6):518-23.
Silva-García CG. Devo-Aging: Intersections Between Development and Aging. Geroscience. 2023;45(4):2145-59.
Singer MA. The Origins of Aging: Evidence that Aging is an Adaptive Phenotype. Curr Aging Sci. 2016;9(2):95-115.
Somes J. The Loneliness of Aging. J Emerg Nurs. 2021;47(3):469-75.
Sorpreso IC, Soares Júnior JM, Fonseca AM, Baracat EC. Female aging. Rev Assoc Med Bras (1992). 2015;61(6):553-6.
Sorrentino JA, Sanoff HK, Sharpless NE. Defining the toxicology of aging. Trends Mol Med. 2014;20(7):375-84.
Sreekantaswamy SA, Butler DC, Shah AA. Reframing aging in dermatology: The role of the dermatologist in healthy aging. Int J Womens Dermatol. 2021;7(5Part A):529-32.
Tabatabaie V, Surks MI. The aging thyroid. Curr Opin Endocrinol Diabetes Obes. 2013;20(5):455-9.
Tabibzadeh S. CircadiOmic medicine and aging. Ageing Res Rev. 2021;71:101424.
Takahashi Y, Kuro OM, Ishikawa F. Aging mechanisms. Proc Natl Acad Sci U S A. 2000;97(23):12407-8.
Tan Q, Liang N, Zhang X, Li J. Dynamic Aging: Channeled Through Microenvironment. Front Physiol. 2021;12:702276.
Terlecky SR, Koepke JI, Walton PA. Peroxisomes and aging. Biochim Biophys Acta. 2006;1763(12):1749-54.
Theurey P, Pizzo P. The Aging Mitochondria. Genes (Basel). 2018;9(1).
Ting KK, Coleman P, Zhao Y, Vadas MA, Gamble JR. The aging endothelium. Vasc Biol. 2021;3(1):R35-r47.
Tobin DJ. Introduction to skin aging. J Tissue Viability. 2017;26(1):37-46.
Tower J. Hsps and aging. Trends Endocrinol Metab. 2009;20(5):216-22.
Travin DY, Feniouk BA. Aging in Birds. Biochemistry (Mosc). 2016;81(12):1558-63.
Tuite DJ, Renström PA, O'Brien M. The aging tendon. Scand J Med Sci Sports. 1997;7(2):72-7.
Turner GA, Bhogal RK. Hair and Aging. Skinmed. 2016;14(5):338-43.
Vaillant GE, Mukamal K. Successful aging. Am J Psychiatry. 2001;158(6):839-47.
Van Avondt K, Strecker JK, Tulotta C, Minnerup J, Schulz C, Soehnlein O. Neutrophils in aging and aging-related pathologies. Immunol Rev. 2023;314(1):357-75.
Vasto S, Scapagnini G, Bulati M, Candore G, Castiglia L, Colonna-Romano G, et al. Biomarkes of aging. Front Biosci (Schol Ed). 2010;2(2):392-402.
Vijg J, Calder RB. Transcripts of aging. Trends Genet. 2004;20(6):221-4.
Visvanathan R. Anorexia of Aging. Clin Geriatr Med. 2015;31(3):417-27.
Vogelaere P, Pereira C. Thermoregulation and aging. Rev Port Cardiol. 2005;24(5):747-61.
Vulliamy TJ. Premature aging. Cell Mol Life Sci. 2009;66(18):3091-4.
Wakale S, Wu X, Sonar Y, Sun A, Fan X, Crawford R, et al. How are Aging and Osteoarthritis Related? Aging Dis. 2023;14(3):592-604.
Waljee JF, Greenfield LJ. Aging and surgeon performance. Adv Surg. 2007;41:189-98.
Wallis ZK, Williams KC. Monocytes in HIV and SIV Infection and Aging: Implications for Inflamm-Aging and Accelerated Aging. Viruses. 2022;14(2).
Wang M. Neurosteroids and brain aging. Minerva Ginecol. 2013;65(6):587-605.
Wang M, Monticone RE, McGraw KR. Proinflammation, profibrosis, and arterial aging. Aging Med (Milton). 2020;3(3):159-68.
Wang PS, Lo MJ, Kau MM. Glucocorticoids and aging. J Formos Med Assoc. 1997;96(10):792-801.
Wang Y, Dong C, Han Y, Gu Z, Sun C. Immunosenescence, aging and successful aging. Front Immunol. 2022;13:942796.
Weale RA. Aging and vision. Vision Res. 1986;26(9):1507-12.
Weidner CI, Wagner W. The epigenetic tracks of aging. Biol Chem. 2014;395(11):1307-14.
Wen SW, Wong CHY. Aging- and vascular-related pathologies. Microcirculation. 2019;26(2):e12463.
Wessells RJ, Bodmer R. Cardiac aging. Semin Cell Dev Biol. 2007;18(1):111-6.
Wiggins JE. Aging in the glomerulus. J Gerontol A Biol Sci Med Sci. 2012;67(12):1358-64.
Wilkerson WR, Sane DC. Aging and thrombosis. Semin Thromb Hemost. 2002;28(6):555-68.
Williams GR, Rier HN, McDonald A, Shachar SS. Sarcopenia & aging in cancer. J Geriatr Oncol. 2019;10(3):374-7.
Williams L. Aging cebidae. Interdiscip Top Gerontol. 2008;36:49-61.
Wing EJ. HIV and aging. Int J Infect Dis. 2016;53:61-8.
Winkler AA, Downs BW. Aging male rhinoplasty. Facial Plast Surg Clin North Am. 2008;16(3):329-35.
Wolak T, Paran E. Can carotenoids attenuate vascular aging? Vascul Pharmacol. 2013;59(3-4):63-6.
Wood JM. Aging, driving and vision. Clin Exp Optom. 2002;85(4):214-20.
Wu J, Liu Y, Song Y, Wang L, Ai J, Li K. Aging conundrum: A perspective for ovarian aging. Front Endocrinol (Lausanne). 2022;13:952471.
Wu Z, Yu J, Zhu A, Nakanishi H. Nutrients, Microglia Aging, and Brain Aging. Oxid Med Cell Longev. 2016;2016:7498528.
Xia X, Wang Y, Yu Z, Chen J, Han JJ. Assessing the rate of aging to monitor aging itself. Ageing Res Rev. 2021;69:101350.
Xu K, Guo Y, Li Z, Wang Z. Aging Biomarkers and Novel Targets for Anti-Aging Interventions. Adv Exp Med Biol. 2019;1178:39-56.
Xu W, Wong G, Hwang YY, Larbi A. The untwining of immunosenescence and aging. Semin Immunopathol. 2020;42(5):559-72.
Yang C, Zhang W, Dong X, Fu C, Yuan J, Xu M, et al. A natural product solution to aging and aging-associated diseases. Pharmacol Ther. 2020;216:107673.
Yankner BA, Lu T, Loerch P. The aging brain. Annu Rev Pathol. 2008;3:41-66.
Yeo EJ. Hypoxia and aging. Exp Mol Med. 2019;51(6):1-15.
Yorkston KM, Bourgeois MS, Baylor CR. Communication and aging. Phys Med Rehabil Clin N Am. 2010;21(2):309-19.
Yung RL, Julius A. Epigenetics, aging, and autoimmunity. Autoimmunity. 2008;41(4):329-35.
Zec RF. The neuropsychology of aging. Exp Gerontol. 1995;30(3-4):431-42.
Zheng R, Zhang Y, Zhang K, Yuan Y, Jia S, Liu J. The Complement System, Aging, and Aging-Related Diseases. Int J Mol Sci. 2022;23(15).
Zhou XJ, Rakheja D, Yu X, Saxena R, Vaziri ND, Silva FG. The aging kidney. Kidney Int. 2008;74(6):710-20.
Zucchero T, Ahmed S. Genetics of proliferative aging. Exp Gerontol. 2006;41(10):992-1000.
Farrokhi M, Khouzani SJ, Farrokhi M, Jalayeri H, Faranoush P, Babaei M, et al. Artificial Intelligence and Deep Learning for Screening and Risk Assessment of Cancers. Kindle. 2024;4(1):1-140.
Farrokhi M, Rigi A, Mangouri A, Fadaei M, Shabani E, Mashouf P et al. Role of Antioxidants in Autoimmune Diseases. Kindle. 2021;1(1):1-107.
Farrokhi M, Shabani S, Rigi A, Seighalani HH, Pazhooha M, Bagheri S et al. Academic Textbook: Anatomy, Pathophysiology, and Treatment of Pain. Kindle. 2023;3(1):1-123.
Farrokhi M, Vafaei S, Bidares M, Siami H, Rigi A, Hannaniyan M et al. Diagnosis and Treatment of Manifestations of COVID-19. Kindle. 2021;1(1):1-170.
Yarmohammadi B, Rigi A, Sahebkar F, Ahadiat S-A, Gharei F, Heydarian P et al. Guidelines for Providing Services in Medical Departments During the COVID-19 Pandemic. Kindle. 2022;2(1):1-193.
Ahadiat S-A, Shirazinia M, Shirazinia S, Garousi S, Mottahedi M, Jalali AB et al. Role of Telemedicine in Management of Patients During the COVID-19 Pandemic. Kindle. 2022;2(1):1-191.
Abadi SAH, Atbaei R, Forouhi M, Falaverjani HG, Moazamiyanfar R, Rezaei M et al. Preventive and Therapeutic Approaches in Medical Departments During the COVID-19 Pandemic. Kindle. 2022;2(1):1-216.
Ahadiat S-A, Ghazalgoo A, Abadi SAH, Falaverjani HG, Bagherianlemraski M, Namazifar F et al. Role of Vitamin D in Pathogenesis, Diagnosis, and Treatment of Inflammatory Diseases. Kindle. 2022;2(1):1-119.
Ahadiat S-A, Atighi J, Forouhi M, Mashatan N, Ghahremaniyeh Z, Radmanesh M et al. Diagnosis and Management of Complications of COVID-19. Kindle. 2022;2(1):1-113.
Tabatabaei SOH, Moazamiyanfar R, Fard AM, Salemi MH, Masjedi MNK, Yazdani Y et al. Academic Textbook: The Role of Melatonin in Pathogenesis and Treatment of Autoimmune Diseases. Kindle. 2023;3(1):1-126.
Ahadiat S-A, Falaverjani HG, Shabani M, Abadi SAH, Moazamiyanfar R, Rajabi SK et al. The Role of Stem Cells in Treatment of Autoimmune Diseases. Kindle. 2022;2(1):1-136.
Fard AM, Nikbakht T, Babaei N, Pouyamanesh M, Afzalian A, Kharazmkia A et al. Role of Medicinal Plants in Treatment of Inflammatory Diseases. Kindle. 2022;2(1):1-139.
Ahadiat S-A, Barati R, Moghadam NS, Samami E, Ghiabi S, Alyari M et al. Role of Oxidative Stress and Antioxidants in Malignancies. Kindle. 2022;2(1):1-122.
Ahadiat S-A, Kamrani K, Fard AM, Bagherianlemraski M, Rahimpour E, Jamali M et al. Role of Blood Groups in Risk, Severity, Prognosis, and Response to Treatment of the Diseases. Kindle. 2022;2(1):1-130.
Ghalamkarpour N, Fard AM, Babazadeh A, Nikseresht H, Feyzmanesh A, Soltani R et al. Role of Biomarkers in Risk, Diagnosis, Response to Treatment, and Prognosis of the Autoimmune Diseases. Kindle. 2022;2(1):1-124.
Talaie R, Fard SS, Forouhi M, Fard AM, Fard TM, Dadashzadehasl N et al. Applications, Limitations, and Guidelines for the Use of Telemedicine in Medical Departments. Kindle. 2022;2(1):1-118.
Rahmani E, Fard AM, Baghsheikhi H, Hosseini Z, Mashaollahi A, Atighi J et al. Role of Selenium in Pathogenesis and Treatment of the Autoimmune Diseases. Kindle. 2022;2(1):1-131.
Poudineh S, Poudineh M, Roohinezhad R, Khorram R, Fard AM, Barzegar F et al. Role of Vitamins in Pathogenesis and Treatment of Cancers. Kindle. 2023;3(1):1-110.
Poudineh M, Poudineh S, Hosseini Z, Pouramini S, Fard SS, Fadavian H et al. Risk Factors for the Development of Cancers. Kindle. 2023;3(1):1-118.
Amini N, Azimzadeh M, Dosar MD, Fard AM, Habibzadeh N, Yahyazadehjasour S et al. Role of Microbiome, Infection, and Inflammation in Autoimmune Diseases. Kindle. 2023;3(1):1-102.
Taheri F, Farrokhi M, Fard AM, Rahmani E, Soltani R, Shamsedanesh S et al. Role of Micronutrients and Nutrition in Prevention and Treatment of Cancers. Kindle. 2023;3(1):1-102.
Taheri F, Rahmani E, Fard SS, Rezaei M, Ayati A, Farhoudian A et al. Aging Process and Related Diseases. Kindle. 2023;3(1):1-117.
Rahmani E, Rezaei M, Tavakoli R, Ghadirzadeh E, Sarnaghy FJ, Khorram R et al. Role of Regenerative Medicine in the Treatment of Diseases. Kindle. 2023;3(1):1-184.
Rezaei M, Rahmani E, Khouzani SJ, Rahmannia M, Ghadirzadeh E, Bashghareh P et al. Role of Artificial Intelligence in the Diagnosis and Treatment of Diseases. Kindle. 2023;3(1):1-160.
Farrokhi M, Taheri F, Khouzani PJ, Rahmani E, Tavakoli R, Fard AM et al. Role of Precision Medicine and Personalized Medicine in the Treatment of Diseases. Kindle. 2023;3(1):1-164.
Farrokhi M, Taheri F, Karami E, Khorram R, Sarnaghy FJ, Mirbolook A et al. Effects of Environmental Factors and Epigenetic on Health and the Development of Diseases. Kindle. 2023;3(1):1-186.
Farrokhi M, Taheri F, Moeini A, Farrokhi M, Rabiei S, Farahmandsadr M et al. Sex and Gender Differences in the Pathogenesis and Treatment of Diseases. Kindle. 2023;3(1):1-168.
Rezaei T, Khouzani PJ, Khouzani SJ, Fard AM, Rashidi S, Ghazalgoo A et al. Integrating Artificial Intelligence into Telemedicine: Revolutionizing Healthcare Delivery. Kindle. 2023;3(1):1-161.
Farrokhi M, Moeini A, Taheri F, Farrokhi M, Mostafavi M, Ardakan AK et al. Artificial Intelligence in Cancer Care: From Diagnosis to Prevention and Beyond. Kindle. 2023;3(1):1-149.
Rezaei M, Saei S, Khouzani SJ, Rostami ME, Rahmannia M, Manzelat AMR, et al. Emerging Technologies in Medicine: Artificial Intelligence, Robotics, and Medical Automation. Kindle. 2023;3(1):1-184.
Farrokhi M, Moeini A, Taheri F, Farrokhi M, Khodashenas M, Babaei M, Khouzani PJ, Nikseresht H, Shafiei D, Shayankia G, Shayankia A. AI-assisted Screening and Prevention Programs for Diseases. Kindle. 2023 Dec 12;3(1):1-209.
