Global Health Challenges
Keywords:
Health, Challenges, Global, MedicineAbstract
Global health faces numerous challenges that significantly impact populations worldwide. These challenges stem from a combination of epidemiological, social, economic, and environmental factors, requiring coordinated international efforts to address them effectively. Non-communicable diseases (NCDs), such as cardiovascular diseases, diabetes, cancer, and chronic respiratory diseases, are among the leading causes of death globally. Their rise is fueled by aging populations, urbanization, unhealthy diets, sedentary lifestyles, and tobacco and alcohol use. These diseases strain healthcare systems, particularly in low- and middle-income countries (LMICs), where resources are often insufficient to manage their growing burden. Addressing these requires preventive measures, early detection, and equitable access to treatment. Infectious diseases remain a persistent challenge, particularly in LMICs. Diseases such as malaria, tuberculosis, and HIV/AIDS continue to affect millions. Additionally, global threats like antimicrobial resistance and emerging infections, such as COVID-19, highlight vulnerabilities in public health systems and the need for global preparedness, robust surveillance, and rapid response mechanisms. Healthcare disparities exacerbate these challenges. Many regions lack adequate healthcare infrastructure, trained professionals, and affordable treatments. Inequities in access to care are stark, particularly in rural areas and among marginalized populations, perpetuating poor health outcomes. Environmental factors, including climate change, air pollution, and inadequate water and sanitation, also contribute to the global health burden. Rising temperatures and extreme weather events increase the spread of vector-borne diseases, exacerbate food insecurity, and displace vulnerable populations. Addressing global health challenges requires collaborative international policies, sustainable financing, and investments in public health infrastructure and education. A multi-sectoral approach is essential to tackle these interconnected issues, promoting health equity and resilience worldwide.
References
WHO Guidelines Approved by the Guidelines Review Committee. WHO Guidelines on Hand Hygiene in Health Care: First Global Patient Safety Challenge Clean Care Is Safer Care. Geneva: World Health Organization
Copyright © 2009, World Health Organization.; 2009.
Abstracts of the 3rd World Psoriasis & Psoriatic Arthritis Conference 2012: "Psoriasis-a global health challenge" : Stockholm, Sweden, June 27-July 1, 2012. Dermatol Ther (Heidelb). 2012;2(Suppl 1):10.
Akhoundi M, Zumelzu C, Sereno D, Marteau A, Brun S, Jan J, et al. Bed Bugs (Hemiptera, Cimicidae): A Global Challenge for Public Health and Control Management. Diagnostics (Basel). 2023;13(13).
Anand U, Vithanage M, Rajapaksha AU, Dey A, Varjani S, Bontempi E. Inapt management of menstrual hygiene waste (MHW): An urgent global environmental and public health challenge in developed and developing countries. Heliyon. 2022;8(7):e09859.
Arababadi MK, Hassanshahi G, Pourfathollah AA, Zarandi ER, Kennedy D. Post-transfusion occult hepatitis B (OBI): a global challenge for blood recipients and health authorities. Hepat Mon. 2011;11(9):714-8.
Arredondo A. Diabetes: a global challenge with high economic burden for public health systems and society. Am J Public Health. 2013;103(2):e1-2.
Arredondo A, Azar A, Recamán AL. Diabetes, a global public health challenge with a high epidemiological and economic burden on health systems in Latin America. Glob Public Health. 2018;13(7):780-7.
Arrizabalaga J. [The challenge of (re)emerging diseases, the limits of the biomedical response and the new paradigm of global health]. Hist Cienc Saude Manguinhos. 2021;28(1):255-81.
Askheim C, Heggen K, Engebretsen E. Politics and Power in Global Health: The Constituting Role of Conflicts: Comment on "Navigating Between Stealth Advocacy and Unconscious Dogmatism: The Challenge of Researching the Norms, Politics and Power of Global Health". Int J Health Policy Manag. 2015;5(2):117-9.
Bruce IN. Health inequalities and systemic lupus erythematosus: a global challenge. Rheumatology (Oxford). 2023;62(Suppl 1):i1-i3.
Buonsenso D, De Rose C. Implementation of lung ultrasound in low- to middle-income countries: a new challenge global health? Eur J Pediatr. 2022;181(1):1-8.
Byass P. The global burden of liver disease: a challenge for methods and for public health. BMC Med. 2014;12:159.
Calderon J, Rojas G. Integration of mental health into primary care: a Chilean perspective on a global challenge. BJPsych Int. 2016;13(1):20-1.
Chen B, Kan H. Air pollution and population health: a global challenge. Environ Health Prev Med. 2008;13(2):94-101.
Chow CK, Gupta R. Blood pressure control: a challenge to global health systems. Lancet. 2019;394(10199):613-5.
Cluver L. Solving the global challenge of adolescent mental ill-health. Lancet Child Adolesc Health. 2020;4(8):556-7.
Conceição LSR, Gomes CVC, Carvalho VO. Comment on: "The Challenge of Maintaining Metabolic Health During a Global Pandemic". Sports Med. 2020;50(11):2063-4.
Cossarizza A, De Biasi S, Guaraldi G, Girardis M, Mussini C. SARS-CoV-2, the Virus that Causes COVID-19: Cytometry and the New Challenge for Global Health. Cytometry A. 2020;97(4):340-3.
Cotch MF, Freeman EE. Health care services: addressing the global challenge of universal eye health. Ophthalmic Epidemiol. 2013;20(5):255-7.
Cuestas ML, Minassian ML. [Emerging and re-emerging viruses: A new challenge for global health in this millennium]. Rev Argent Microbiol. 2020;52(1):1-3.
D'Haese PSC, Van Rompaey V, De Bodt M, Van de Heyning P. Severe Hearing Loss in the Aging Population Poses a Global Public Health Challenge. How Can We Better Realize the Benefits of Cochlear Implantation to Mitigate This Crisis? Front Public Health. 2019;7:227.
Dan S, Pant M, Upadhyay SK. The Case Fatality Rate in COVID-19 Patients With Cardiovascular Disease: Global Health Challenge and Paradigm in the Current Pandemic. Curr Pharmacol Rep. 2020;6(6):315-24.
de Azeredo Passos VM, Champs APS, Teixeira R, Lima-Costa MFF, Kirkwood R, Veras R, et al. The burden of disease among Brazilian older adults and the challenge for health policies: results of the Global Burden of Disease Study 2017. Popul Health Metr. 2020;18(Suppl 1):14.
de Leon Siantz ML. Feminization of migration: a global health challenge. Glob Adv Health Med. 2013;2(5):12-4.
Deb AK, Kanungo S, Nair GB, Narain JP. The challenge of pneumonia & acute diarrhoea at global, regional & national levels: time to refocus on a top most priority health problem. Indian J Med Res. 2011;133(2):128-30.
Dlima SD, Hall A, Aminu AQ, Akpan A, Todd C, Vardy E. Frailty: a global health challenge in need of local action. BMJ Glob Health. 2024;9(8).
Dutta S, Jiang J, Ghosh S, Patel S, Bhikadiya C, Lowe R, et al. An idea to explore: How an interdisciplinary undergraduate course exploring a global health challenge in molecular detail enabled science communication and collaboration in diverse audiences. Biochem Mol Biol Educ. 2023;51(2):137-45.
Esser DE, Ward PS. Ageing as a global public health challenge: from complexity reduction to aid effectiveness. Glob Public Health. 2013;8(7):745-68.
Fatima K, Shabbir O, Ochani RK. Emergence of a highly resistant typhoid strain: a new global health challenge. Infez Med. 2019;27(1):109-10.
Ferraz D, Barreira D. Preparing for future pandemics while responding to the current ones in the midst of a planetary climate crisis: Can we face this triple global health challenge? Glob Public Health. 2024;19(1):2351593.
Flaño Olivos J, Cabieses B. [Curricular training in global health in Chile: a pending challenge?]. Rev Med Chil. 2017;145(9):1225-7.
Forman L. The Ghost Is the Machine: How Can We Visibilize the Unseen Norms and Power of Global Health? Comment on "Navigating Between Stealth Advocacy and Unconscious Dogmatism: The Challenge of Researching the Norms, Politics and Power of Global Health". Int J Health Policy Manag. 2015;5(3):197-9.
Franco E, Pettinicchio V, Zorzoli E. The evolution of the burden of viral hepatitis from 1990 to 2013: still an open challenge to global public health policy. Hepatobiliary Surg Nutr. 2017;6(4):277-9.
Gibbs EP, Anderson TC. One World - One Health' and the global challenge of epidemic diseases of viral aetiology. Vet Ital. 2009;45(1):35-44.
Ginsburg O, Bray F, Coleman MP, Vanderpuye V, Eniu A, Kotha SR, et al. The global burden of women's cancers: a grand challenge in global health. Lancet. 2017;389(10071):847-60.
Gottesfeld P. The Lead Battery: A Growing Global Public Health Challenge. Am J Public Health. 2017;107(7):1049-50.
Gutenbrunner C, Negrini S, Kiekens C, Zampolini M, Nugraha B. The Global Disability Action Plan 2014-2021 of the World Health Organisation (WHO): a major step towards better health for all people with disabilities. Chance and challenge for Physical and Rehabilitation Medicine (PRM). Eur J Phys Rehabil Med. 2015;51(1):1-4.
Hanefeld J. Advancing Global Health - The Need for (Better) Social Science Comment on "Navigating Between Stealth Advocacy and Unconscious Dogmatism: The Challenge of Researching the Norms, Politics and Power of Global Health". Int J Health Policy Manag. 2016;5(4):279-81.
Institute of Medicine Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing C. The National Academies Collection: Reports funded by National Institutes of Health. In: Fuster V, Kelly BB, editors. Promoting Cardiovascular Health in the Developing World: A Critical Challenge to Achieve Global Health. Washington (DC): National Academies Press (US)
Copyright © 2010, National Academy of Sciences.; 2010.
Joshi A, Perin DM. Gaps in the existing public health informatics training programs: a challenge to the development of a skilled global workforce. Perspect Health Inf Manag. 2012;9(Fall):1-13.
Joshi R, Jan S, Wu Y, MacMahon S. Global inequalities in access to cardiovascular health care: our greatest challenge. J Am Coll Cardiol. 2008;52(23):1817-25.
Jürgens R, Csete J, Lim H, Timberlake S, Smith M. Human Rights and the Global Fund to Fight AIDS, Tuberculosis and Malaria: How Does a Large Funder of Basic Health Services Meet the Challenge of Rights-Based Programs? Health Hum Rights. 2017;19(2):183-95.
Kennedy S. Frontiers in Global Women's Health: Choose to Challenge. Front Glob Womens Health. 2021;2:676178.
Khunti K, Chudasama YV, Gregg EW, Kamkuemah M, Misra S, Suls J, et al. Diabetes and Multiple Long-term Conditions: A Review of Our Current Global Health Challenge. Diabetes Care. 2023;46(12):2092-101.
Kickbusch I. Politics or Technocracy - What Next for Global Health? Comment on "Navigating Between Stealth Advocacy and Unconscious Dogmatism: The Challenge of Researching the Norms, Politics and Power of Global Health". Int J Health Policy Manag. 2015;5(3):201-4.
King AJ, Burke LM, Halson SL, Hawley JA. The Challenge of Maintaining Metabolic Health During a Global Pandemic. Sports Med. 2020;50(7):1233-41.
Lai S, Chen Q, Li Z. Human Brucellosis: An Ongoing Global Health Challenge. China CDC Wkly. 2021;3(6):120-3.
Lazarus JV, Mark HE, Villota-Rivas M, Palayew A, Carrieri P, Colombo M, et al. The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge? J Hepatol. 2022;76(4):771-80.
Le Loup G, Fleury S, Camargo K, Larouzé B. International institutions, global health initiatives and the challenge of sustainability: lessons from the Brazilian AIDS programme. Trop Med Int Health. 2010;15(1):5-10.
Liu Q, Chen M, Zhou XN. Chagas Disease - An Underestimated Global Public Health Challenge. China CDC Wkly. 2020;2(20):362-3.
Lodeiro C, Capelo-Martínez JL, Santos HM, Oliveira E. Impacts of environmental issues on health and well-being: a global pollution challenge. Environ Sci Pollut Res Int. 2021;28(15):18309-13.
Margolis SA. Diabetic foot - A global health challenge. Aust J Gen Pract. 2020;49(5):237.
Mariani AW, Pêgo-Fernandes PM. Global Health Governance: a rising challenge. Sao Paulo Med J. 2013;131(5):287-8.
Marten R. Global Health Warning: Definitions Wield Power Comment on "Navigating Between Stealth Advocacy and Unconscious Dogmatism: The Challenge of Researching the Norms, Politics and Power of Global Health". Int J Health Policy Manag. 2015;5(3):207-9.
Martin K. Global Health's Grand Challenge:: Achieving healthy populations and a sustainable planet. Dela J Public Health. 2018;4(4):56-7.
Martin K, Landrigan PJ. Global Health's Grand Challenge: A Healthy Planet and Healthy People. Ann Glob Health. 2016;82(3):317-8.
McInnes C, Kamradt-Scott A, Lee K, Reubi D, Roemer-Mahler A, Rushton S, et al. Framing global health: the governance challenge. Glob Public Health. 2012;7 Suppl 2:S83-94.
McIntosh AM, Stewart R, John A, Smith DJ, Davis K, Sudlow C, et al. Data science for mental health: a UK perspective on a global challenge. Lancet Psychiatry. 2016;3(10):993-8.
Mirmohammadsadegh N, Mashreghi Mohammadi N, Amin M. Potential Treponema denticola-based periodontal vaccine to resolve a global public health challenge: a narrative literature review. Expert Rev Vaccines. 2022;21(5):621-32.
Murphy J. Health informatics education: a global challenge. Health Info Libr J. 2009;26(1):72-6.
Ndabashinze R, Simiyu BW, Sah S, Mehta R, Bushi G, Balaraman AK, et al. Zambia's first Mpox case: An emerging challenge in Southern Africa amid a global health crisis. New Microbes New Infect. 2024;62:101536.
Ogbuanya AU, Ugwu NB, Kwento N, Enyanwuma EI, Anyigor FF, Oko U. Abdominal Injuries from Civilian Conflicts: An Emerging Global Health Challenge in Rural Southeast Nigeria. Ann Glob Health. 2023;89(1):4.
Oladeji BD, Gureje O. Brain drain: a challenge to global mental health. BJPsych Int. 2016;13(3):61-3.
Oliveira SD, Almodóvar S, Butrous G, De Jesus Perez V, Fabro A, Graham BB, et al. Infection and pulmonary vascular diseases consortium: United against a global health challenge. Pulm Circ. 2024;14(4):e70003.
Ooms G. Navigating Between Stealth Advocacy and Unconscious Dogmatism: The Challenge of Researching the Norms, Politics and Power of Global Health. Int J Health Policy Manag. 2015;4(10):641-4.
Palatnik-de-Sousa CB, Day MJ. One Health: the global challenge of epidemic and endemic leishmaniasis. Parasit Vectors. 2011;4:197.
Paradis G, Chiolero A. The cardiovascular and chronic diseases epidemic in low- and middle-income countries: a global health challenge. J Am Coll Cardiol. 2011;57(17):1775-7.
Pawankar R. The unmet global health need of severe and complex allergies: meeting the challenge. World Allergy Organ J. 2012;5(2):20-1.
Popkin BM. Does global obesity represent a global public health challenge? Am J Clin Nutr. 2011;93(2):232-3.
Quinn SC, Kumar S. Health inequalities and infectious disease epidemics: a challenge for global health security. Biosecur Bioterror. 2014;12(5):263-73.
Raiten DJ, Bremer AA. Exploring the intersection of climate/environmental change, food systems, nutrition, and health: global challenge, opportunity, or both? Am J Clin Nutr. 2023;117(2):224-6.
Riaño Galán I. [Pediatric global health: the challenge of moving from the intolerable to the improvable]. An Pediatr (Barc). 2013;78(2):71-4.
Royston G, Hagar C, Long LA, McMahon D, Pakenham-Walsh N, Wadhwani N. Mobile health-care information for all: a global challenge. Lancet Glob Health. 2015;3(7):e356-7.
Rubio Herrera MA, Bretón Lesmes I. [Obesity in the COVID era: A global health challenge]. Endocrinol Diabetes Nutr. 2021;68(2):123-9.
Rubio Herrera MA, Bretón Lesmes I. Obesity in the COVID era: A global health challenge. Endocrinol Diabetes Nutr (Engl Ed). 2021;68(2):123-9.
Saito H, Funaki T, Kamata K, Ide K, Nakamura S, Ichimura Y, et al. Infectious Disease Emergency Specialist (IDES) Training Program in Japan: an innovative governmental challenge to respond to global public health emergencies. Glob Health Med. 2020;2(1):44-7.
Saltman DC, Kidd MR, Jackson D, Cleary M. Transportability of tertiary qualifications and CPD: a continuing challenge for the global health workforce. BMC Med Educ. 2012;12:51.
Shafiq N, Pandey AK, Malhotra S, Holmes A, Mendelson M, Malpani R, et al. Shortage of essential antimicrobials: a major challenge to global health security. BMJ Glob Health. 2021;6(11).
Shenoy A, Ismaily M, Bajaj M. Diabetes and covid-19: a global health challenge. BMJ Open Diabetes Res Care. 2020;8(1).
Siem H, Haffeld J, Lie SO, Røttingen JA. Global health--a challenge for us all. Tidsskr Nor Laegeforen. 2011;131(17):1636.
Spirito F, Guida A, Caponio VCA, Lo Muzio L. Monkeypox: A New Challenge for Global Health System? Life (Basel). 2023;13(6).
Sridhar D. Who sets the global health research agenda? The challenge of multi-bi financing. PLoS Med. 2012;9(9):e1001312.
Stephen C. Collective global amnesia. One Health's greatest challenge. Can Vet J. 2021;62(12):1345-6.
Surendran SN, Jayadas TTP, Sivabalakrishnan K, Santhirasegaram S, Karvannan K, Weerarathne TC, et al. Development of the major arboviral vector Aedes aegypti in urban drain-water and associated pyrethroid insecticide resistance is a potential global health challenge. Parasit Vectors. 2019;12(1):337.
Swartz L, Kilian S, Twesigye J, Attah D, Chiliza B. Language, culture, and task shifting--an emerging challenge for global mental health. Glob Health Action. 2014;7:23433.
Velazquez JA, Negrutiu I. Agriculture and global physicochemical deregulation: planetary boundaries that challenge planetary health. Lancet Planet Health. 2019;3(1):e10-e1.
Waage J, Cornelsen L, Dangour AD, Green R, Häsler B, Hull E, et al. Integrating Agriculture and Health Research for Development: LCIRAH as an Interdisciplinary Programme to Address a Global Challenge. Glob Chall. 2019;3(4):1700104.
Wells JCK. Promoting ethnic parity in health, leaving behind "race": a challenge for the global community in 2020. Am J Clin Nutr. 2020;112(3):505-6.
Xu Z, Liu K, Gao GF. Omicron variant of SARS-CoV-2 imposes a new challenge for the global public health. Biosaf Health. 2022;4(3):147-9.
Young AJ, Terry RF, Røttingen JA, Viergever RF. Global trends in health research and development expenditures--the challenge of making reliable estimates for international comparison. Health Res Policy Syst. 2015;13:7.
Zaami S, Busardò FP, Pichini S, Pacifici R, Marinelli E. The value of toxicological and forensic analyses in the global challenge to health risks caused by new psychoactive substances. Eur Rev Med Pharmacol Sci. 2019;23(14):6008-10.
Zimba O, Gasparyan AY. Refugee Health: A Global and Multidisciplinary Challenge. J Korean Med Sci. 2023;38(6):e60.
Al-Abri SS, Al-Rawahi B, Abdelhady D, Al-Abaidani I. Effective vaccine management and Oman's healthcare system's challenge to maintain high global standards. J Infect Public Health. 2018;11(5):742-4.
Aldous AR, Tear T, Fernandez LE. The global challenge of reducing mercury contamination from artisanal and small-scale gold mining (ASGM): evaluating solutions using generic theories of change. Ecotoxicology. 2024;33(4-5):506-17.
Aletta F, Osborn D. The COVID-19 global challenge and its implications for the environment - what we are learning. UCL Open Environ. 2020;2:e008.
Amarakoon M, Homer-Vanniasinkam S, Edirisinghe M. A Global Challenge: Sustainability of Submicrometer PEO and PVP Fiber Production. Glob Chall. 2023;7(9):2300152.
Anthis NJ, Kavanaugh-Lynch MHE. The Global Challenge to Prevent Breast Cancer: Surfacing New Ideas to Accelerate Prevention Research. Int J Environ Res Public Health. 2020;17(4).
Anthony KRN, Helmstedt KJ, Bay LK, Fidelman P, Hussey KE, Lundgren P, et al. Interventions to help coral reefs under global change-A complex decision challenge. PLoS One. 2020;15(8):e0236399.
Arends SJR, Rhomberg PR, Cotroneo N, Rubio A, Flamm RK, Mendes RE. Antimicrobial Activity Evaluation of Tebipenem (SPR859), an Orally Available Carbapenem, against a Global Set of Enterobacteriaceae Isolates, Including a Challenge Set of Organisms. Antimicrob Agents Chemother. 2019;63(6).
Asawapaithulsert P, Pisutsan P, Matsee W. Coincidence of fever following COVID-19 vaccine and endemic tropical diseases: a challenge to clinicians during the global rollout of COVID-19 vaccination. J Travel Med. 2021;28(6).
Basso V, De Freitas Pereira M, Maillard F, Mallerman J, Mangeot-Peter L, Zhang F, et al. Facing global change: the millennium challenge for plant scientists: 41(st) New Phytologist Symposium 'Plant sciences for the future', Nancy, France, April 2018. New Phytol. 2018;220(1):25-9.
Bauersachs J, Koenig T. Peripartum cardiomyopathy - a global challenge. Eur J Heart Fail. 2022;24(9):1737-8.
Benkebil M, Gautier S, Gras-Champel V, Massy N, Micallef J, Valnet Rabier MB. COVID-19 vaccines surveillance in France: a global response to a major national challenge. Anaesth Crit Care Pain Med. 2021;40(3):100866.
Bhidayasiri R, Kalia LV, Bloem BR. Tackling Parkinson's Disease as a Global Challenge. J Parkinsons Dis. 2023;13(8):1277-80.
Bhidayasiri R, Sringean J, Phumphid S, Anan C, Thanawattano C, Deoisres S, et al. The rise of Parkinson's disease is a global challenge, but efforts to tackle this must begin at a national level: a protocol for national digital screening and "eat, move, sleep" lifestyle interventions to prevent or slow the rise of non-communicable diseases in Thailand. Front Neurol. 2024;15:1386608.
Bhutta ZA, Norris SA, Roberts M, Singhal A. The global challenge of childhood obesity and its consequences: what can be done? Lancet Glob Health. 2023;11(8):e1172-e3.
Billiot S, Beltrán R, Brown D, Mitchell FM, Fernandez A. Indigenous Perspectives for Strengthening Social Responses to Global Environmental Changes: A Response to the Social Work Grand Challenge on Environmental Change. J Community Pract. 2019;27(3-4):296-316.
Bisanti L, La Corte C, Dara M, Bertini F, Parisi MG, Chemello R, et al. Global warming-related response after bacterial challenge in Astroides calycularis, a Mediterranean thermophilic coral. Sci Rep. 2024;14(1):8495.
Bledsoe MJ, Grizzle WE. Biospecimen Utilization: A Critical Challenge in Global Bioresource/Biobanking Operations. Biopreserv Biobank. 2019;17(3):201-3.
Bonnet U, Auwärter V, Scherbaum N. Gabapentinoid-related deaths: An alarming global trend or just a special challenge within the long tail of the giant opioid epidemic? Lancet Reg Health Am. 2022;11:100309.
Broeders M, Elfström KM. Importance of International Networking and Comparative Research in Screening to Meet the Global Challenge of Cancer Control. JCO Glob Oncol. 2020;6:180-1.
Buschke FT. Neutral theory reveals the challenge of bending the curve for the post-2020 Global Biodiversity Framework. Ecol Evol. 2021;11(20):13678-83.
Čerlinskaitė K, Hollinger A, Mebazaa A, Cinotti R. Finding the balance between costs and quality in heart failure: a global challenge. Eur J Heart Fail. 2018;20(8):1175-8.
Chauhan V, Thakur S. State of the Globe: Impracticality of Clinical Scores in Acute Undifferentiated Fever: A Global Challenge. J Glob Infect Dis. 2017;9(1):1-2.
Cheng CY, Hao WR, Cheng TH. Esophageal cancer: A global challenge requiring tailored strategies. World J Gastrointest Oncol. 2024;16(7):2881-3.
Chico-Garcia JL, Corral-Corral I, Cruz-Culebras A, Masjuan J. [Acute global amnesia as an exclusive presenting symptom of thalamic infarct: a diagnostic challenge]. Rev Neurol. 2019;68(7):295-300.
Cline MS, Liao RG, Parsons MT, Paten B, Alquaddoomi F, Antoniou A, et al. BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2. PLoS Genet. 2018;14(12):e1007752.
Connell ND. The Challenge of Global Catastrophic Biological Risks. Health Secur. 2017;15(4):345-6.
Cortegiani A, Misseri G, Giarratano A, Bassetti M, Eyre D. The global challenge of Candida auris in the intensive care unit. Crit Care. 2019;23(1):150.
DeVore AD, Allen LA. A Global Challenge and a Global Opportunity for the Heart Failure Community. J Am Coll Cardiol. 2023;82(5):445-7.
Dik JH, Friedrich AW, Nathwani D, Sinha B. Combating the Complex Global Challenge of Antimicrobial Resistance: What can Antimicrobial Stewardship Contribute? Infect Dis Rep. 2017;9(1):7158.
Doherty S, Asghari S, Heeley T, House-Denine M, Hall A, Swab M. Postpartum haemorrhage in rural Indigenous women: scoping review of a global obstetrical challenge. Int J Circumpolar Health. 2022;81(1):2090066.
Donaldson LJ, Kelley ET, Dhingra-Kumar N, Kieny MP, Sheikh A. Medication Without Harm: WHO's Third Global Patient Safety Challenge. Lancet. 2017;389(10080):1680-1.
Downey LA, Hayley AC. Prescription medication use and crash risk: taking responsibility for a new global challenge. Lancet Public Health. 2021;6(6):e349-e50.
Dris R, Agarwal S, Laforsch C. Plastics: From a Success Story to an Environmental Problem and a Global Challenge. Glob Chall. 2020;4(6):2000026.
El-Jardali F, Ataya N, Fadlallah R. Changing roles of universities in the era of SDGs: rising up to the global challenge through institutionalising partnerships with governments and communities. Health Res Policy Syst. 2018;16(1):38.
Farahani AA, Shahali H. New-Onset Transient Global Amnesia: A Clinical Challenge in an Air Medical Transportation Pilot With a History of Coronavirus Disease 2019. Air Med J. 2022;41(4):402-5.
Fauci A, Erbelding E, Whitehead S, Cassetti MC, Handley FG, Gupta R. Dengue vaccine clinical trials in India - An opportunity to inform the global response to a re-emerging disease challenge. Int J Infect Dis. 2019;84s:S4-s6.
Feller L, Khammissa RAG, Altini M, Lemmer J. Noma (cancrum oris): An unresolved global challenge. Periodontol 2000. 2019;80(1):189-99.
Feng Z, Glinskaya E. Aiming Higher: Advancing Public Social Insurance for Longterm Care to Meet the Global Aging Challenge Comment on "Financing Long-term Care: Lessons From Japan". Int J Health Policy Manag. 2020;9(8):356-9.
Finnegan A, Biru B, Taylor A, Rajan S, Udayakumar K, Baumgartner JN. Improving global maternal and newborn survival via innovation: Stakeholder perspectives on the Saving Lives at Birth Grand Challenge. PLoS One. 2021;16(7):e0254589.
Freedman SD, Zaworski K, Pierzynowska K, Pierzynowski S, Gallotto R, Sathe M, et al. Validation of an omega-3 substrate challenge absorption test as an indicator of global fat lipolysis. PLoS One. 2023;18(5):e0284651.
Fuzi M. Editorial: The Global Challenge Posed by the Multiresistant International Clones of Bacterial Pathogens. Front Microbiol. 2017;8:817.
Ghazvini K, Keikha M. What we recognize about omicron sub-lineage BA.2 as a global new challenge? - Correspondence. Int J Surg. 2022;103:106704.
Gill CM, Asempa TE, Tickler IA, Dela Cruz C, Tenover FC, Nicolau DP. Evaluation of the Xpert Carba-R NxG Assay for Detection of Carbapenemase Genes in a Global Challenge Set of Pseudomonas aeruginosa Isolates. J Clin Microbiol. 2020;58(12).
Gomes HJA, Figueredo Junior AR. The Challenge of Making Cardiac Resonance a Global Reality. Arq Bras Cardiol. 2023;120(4):e20230187.
Groom ZC, Zochios V, Protopapas AD. Translating Chagasic dilating cardiomyopathy to surgical therapies: An under published global challenge. SAGE Open Med. 2019;7:2050312119895927.
Guaraldi F, Montalti M, Gori D. The Importance of Mapping Determinants, Attitudes and Beliefs of Vaccine Hesitancy in the Great Challenge of Compulsory Childhood Vaccination Comment on "Convergence on Coercion: Functional and Political Pressures as Drivers of Global Childhood Vaccine Mandates". Int J Health Policy Manag. 2023;12:7614.
Guren MG. The global challenge of colorectal cancer. Lancet Gastroenterol Hepatol. 2019;4(12):894-5.
Hahladakis JN. Delineating the global plastic marine litter challenge: clarifying the misconceptions. Environ Monit Assess. 2020;192(5):267.
Haileamlak A. Tuberculosis Continued as Global Challenge Though the Burden Remained High in Low-Income and High-Income Countries. Ethiop J Health Sci. 2018;28(5):517-8.
Haverroth E, Gobble M, Bradley L, Harris-Gilliam K, Fischer A, Williams C, et al. The Black American experience: Answering the global challenge of broadening participation in STEM/agriculture. Plant Cell. 2024;36(4):807-11.
Hill G, Mason J, Dunn A. Correction to: Contract cheating: an increasing challenge for global academic community arising from COVID-19. Res Pract Technol Enhanc Learn. 2021;16(1):26.
Hill G, Mason J, Dunn A. Contract cheating: an increasing challenge for global academic community arising from COVID-19. Res Pract Technol Enhanc Learn. 2021;16(1):24.
Hoffman SA, Maldonado YA. Emerging and re-emerging pediatric viral diseases: a continuing global challenge. Pediatr Res. 2024;95(2):480-7.
Houlton BZ, Almaraz M, Aneja V, Austin AT, Bai E, Cassman KG, et al. A world of co-benefits: Solving the global nitrogen challenge. Earths Future. 2019;7:1-8.
Hu VH. The global challenge of glaucoma. Community Eye Health. 2021;34(112):61.
Hug SJ, Winkel LHE, Voegelin AA, Berg M, Johnson CA. Arsenic and Other Geogenic Contaminants in Groundwater - A Global Challenge. Chimia (Aarau). 2020;74(7-8):524-37.
Ingabire PM, Semitala F, Kamya MR, Nakanjako D. Delayed Antiretroviral Therapy (ART) Initiation among Hospitalized Adults in a Resource-Limited Settings: A Challenge to the Global Target of ART for 90% of HIV-Infected Individuals. AIDS Res Treat. 2019;2019:1832152.
Isbister GK, Silva A. Addressing the global challenge of snake envenoming. Lancet. 2018;392(10148):619-20.
Iwuji C, Newell ML. Towards control of the global HIV epidemic: Addressing the middle-90 challenge in the UNAIDS 90-90-90 target. PLoS Med. 2017;14(5):e1002293.
Jiang H, Zheng X, Wang L, Du H, Wang P, Bai X. Hantavirus infection: a global zoonotic challenge. Virol Sin. 2017;32(1):32-43.
Kalan ME, Mejia R, Egbe CO, Chopra M, Bteddini D, Jebai R, et al. E-cigarette use in low-income and middle-income countries: opportunity or challenge for global tobacco control. Lancet Glob Health. 2023;11(12):e1855-e6.
Kapur A, Mahmood T, Hod M. FIGO's response to the global challenge of hyperglycemia in pregnancy - toward a global consensus. Gynecol Endocrinol. 2018;34(1):1-3.
Kelly AM, Galligan DT, Salman MD, Osburn BI. The epic challenge of global food security: a compelling mission for veterinary medicine. J Am Vet Med Assoc. 2020;256(6):643-5.
Khan M, Adil SF, Alkhathlan HZ, Tahir MN, Saif S, Khan M, et al. COVID-19: A Global Challenge with Old History, Epidemiology and Progress So Far. Molecules. 2020;26(1).
Kim E, Batul M, Bever S, Mohammed A, Nepomunceno A, Owusu H, et al. The World Smarts STEM Challenge: A promising approach to fostering STEM and global competence skills for adolescents in the US and Ghana. PLoS One. 2024;19(12):e0311116.
Kumar S, Sharma V, Sarkar S, Ludhiadch A. Battle against the pandemic: Emergence of SARS-CoV2 variants and global challenge. Travel Med Infect Dis. 2021;44:102173.
Lambert H, Gupte J, Fletcher H, Hammond L, Lowe N, Pelling M, et al. COVID-19 as a global challenge: towards an inclusive and sustainable future. Lancet Planet Health. 2020;4(8):e312-e4.
Láncos PL, Christián L. Domestic Soft Law Regulation during the COVID-19 Lockdown in Hungary: A Novel Regulatory Approach to a Unique Global Challenge. Eur J Risk Regul. 2021;12(1):77-92.
Li B. Raymond U. Osarogiagbon: lung cancer is a global challenge that needs our close cooperation! Transl Lung Cancer Res. 2018;7(Suppl 4):S393-s6.
Li PK, Chan GC, Chen J, Chen HC, Cheng YL, Fan SL, et al. Tackling Dialysis Burden around the World: A Global Challenge. Kidney Dis (Basel). 2021;7(3):167-75.
Li X, Yang HY. A Global Challenge: Clean Drinking Water. Glob Chall. 2021;5(1):2000125.
Lo Muzio L, Ambosino M, Lo Muzio E, Quadri MFA. SARS-CoV-2 Reinfection Is a New Challenge for the Effectiveness of Global Vaccination Campaign: A Systematic Review of Cases Reported in Literature. Int J Environ Res Public Health. 2021;18(20).
Lokhov PG, Trifonova OP, Maslov DL, Lichtenberg S, Balashova EE. Personal Metabolomics: A Global Challenge. Metabolites. 2021;11(11).
Lou Y, Shen L, Huang Z, Wu Y, Li H, Li G. Does the Effort Meet the Challenge in Promoting Low-Carbon City?-A Perspective of Global Practice. Int J Environ Res Public Health. 2018;15(7).
Macpherson I, Segarra I. Commentary: Grand challenge: ELSI in a changing global environment. Front Genet. 2017;8:135.
Malenfant JH, Brewer TF. Rifampicin Mono-Resistant Tuberculosis-A Review of an Uncommon But Growing Challenge for Global Tuberculosis Control. Open Forum Infect Dis. 2021;8(2):ofab018.
Maphalle LNF, Michniak-Kohn BB, Ogunrombi MO, Adeleke OA. Pediatric Tuberculosis Management: A Global Challenge or Breakthrough? Children (Basel). 2022;9(8).
Marimuthu K, Ng OT, Bagdasarian N, Tambyah PA. The global challenge of carbapenemases and the critical need for more data. Int J Infect Dis. 2019;84:141-2.
Martini M, Barberis I, Gazzaniga V, Icardi G. The fight to end tuberculosis: a global challenge in strong partnership. J Prev Med Hyg. 2020;61(1 Suppl 1):E1-e2.
Mayo X, Liguori G, Iglesias-Soler E, Copeland RJ, Clavel San Emeterio I, Lowe A, et al. The active living gender's gap challenge: 2013-2017 Eurobarometers physical inactivity data show constant higher prevalence in women with no progress towards global reduction goals. BMC Public Health. 2019;19(1):1677.
Meiring JE, Giubilini A, Savulescu J, Pitzer VE, Pollard AJ. Generating the Evidence for Typhoid Vaccine Introduction: Considerations for Global Disease Burden Estimates and Vaccine Testing Through Human Challenge. Clin Infect Dis. 2019;69(Suppl 5):S402-s7.
Melillo JM. Disruption of the global nitrogen cycle: A grand challenge for the twenty-first century : This article belongs to Ambio's 50th Anniversary Collection. Theme: Eutrophication. Ambio. 2021;50(4):759-63.
Meyer H, Pebesma E. Machine learning-based global maps of ecological variables and the challenge of assessing them. Nat Commun. 2022;13(1):2208.
Morales KF, Brown DW, Dumolard L, Steulet C, Vilajeliu A, Ropero Alvarez AM, et al. Seasonal influenza vaccination policies in the 194 WHO Member States: The evolution of global influenza pandemic preparedness and the challenge of sustaining equitable vaccine access. Vaccine X. 2021;8:100097.
Moura-Neto JA, Braga Silva CA, Moura AF, Rocco Suassuna JH. Emergent Arboviruses and Renal Transplantation: A Global Challenge. Kidney Int Rep. 2019;4(5):647-55.
Mowla A. Stroke Care during the COVID-19 Pandemic; A Global Challenge. Iran J Med Sci. 2020;45(5):323-4.
Musa TH, Ahmad T, Khan M, Haroon H, Wei P. Global outbreak of COVID-19: a new challenge? J Infect Dev Ctries. 2020;14(3):244-5.
Napolitano F, De Rosa G, Chay-Canul A, Álvarez-Macías A, Pereira AMF, Bragaglio A, et al. The Challenge of Global Warming in Water Buffalo Farming: Physiological and Behavioral Aspects and Strategies to Face Heat Stress. Animals (Basel). 2023;13(19).
Narancic T, O'Connor KE. Plastic waste as a global challenge: are biodegradable plastics the answer to the plastic waste problem? Microbiology (Reading). 2019;165(2):129-37.
Neiva C. Letter to The Editor: Access to Opioids, A Global Challenge - Impressions of The Brazilian Scenario. Acta Med Port. 2018;31(11):698.
Palma E, Mata L, Cohen K, Evans D, Gandy B, Gaskell N, et al. The city nature challenge: A global citizen science phenomenon contributing to biodiversity knowledge and informing local government practices. Bioscience. 2024;74(4):290-9.
Park J. How can we pay for it all? Understanding the global challenge of financing climate change and sustainable development solutions. J Environ Stud Sci. 2022;12(1):91-9.
Pascher K, Hainz-Renetzeder C, Jagersberger M, Kneissl K, Gollmann G, Schneeweiss GM. Contamination of imported kernels by unapproved genome-edited varieties poses a major challenge for monitoring and traceability during transport and handling on a global scale: inferences from a study on feral oilseed rape in Austria. Front Genome Ed. 2023;5:1176290.
Pereira M, Akinkugbe O, Buckley L, Gilfoyle E, Ibrahim S, McCradden M, et al. Up to the Challenge: Adapting Pediatric Intensive Care During a Global Pandemic. Front Pediatr. 2022;10:910018.
Phang SC, Failler P, Bridgewater P. Addressing the implementation challenge of the global biodiversity framework. Biodivers Conserv. 2020;29(9-10):3061-6.
Phelps LN, Andela N, Gravey M, Davis DS, Kull CA, Douglass K, et al. Madagascar's fire regimes challenge global assumptions about landscape degradation. Glob Chang Biol. 2022;28(23):6944-60.
Printz C. When a global pandemic complicates cancer care: Although oncologists and their patients are accustomed to fighting tough battles against a lethal disease, Coronavirus Disease 2019 (COVID-19) has posed an unprecedented challenge. Cancer. 2020;126(14):3171-3.
Reitzel K, Bennett WW, Berger N, Brownlie WJ, Bruun S, Christensen ML, et al. New Training to Meet the Global Phosphorus Challenge. Environ Sci Technol. 2019;53(15):8479-81.
Reyes AJ, Hosein AS, Ramcharan K, Perot S. Anaphylaxis and other allergic reactions to food: a global challenge. BMJ Case Rep. 2020;13(5).
Ritterbusch J, Severing K, Henheik P, von Graberg T, Li Y, Tröger A. The Challenge of Global Challenges. Glob Chall. 2018;2(1):1870003.
Robertson JS, Chui WK, Genazzani AA, Malan SF, López de la Rica Manjavacas A, Mignot G, et al. The INN global nomenclature of biological medicines: A continuous challenge. Biologicals. 2019;60:15-23.
Robinson K, Cornes JP, Karl JA, Wilson MS, Grimshaw GM. Emotion dysregulation in nonsuicidal self-injury: Dissociations between global self-reports and real-time responses to emotional challenge. J Affect Disord. 2024;362:835-42.
Roohani J, Keikha M. Global challenge with the SARS-CoV-2 omicron BA.2 (B.1.1.529.2) subvariant: Should we be concerned? World J Virol. 2022;11(6):496-501.
Rudolph A, Mitchell J, Barrett J, Sköld H, Taavola H, Erlanson N, et al. Global safety monitoring of COVID-19 vaccines: how pharmacovigilance rose to the challenge. Ther Adv Drug Saf. 2022;13:20420986221118972.
Saran R, Randolph E, Omollo KL. Addressing the global Challenge of NCDs using a Risk Factor approach: voices from around the world. FASEB Bioadv. 2021;3(4):259-65.
Sayegh N, Gross K. Benign prostatic hyperplasia: a global challenge of the ageing population. Lancet Healthy Longev. 2022;3(11):e725-e6.
Sellera FP, Lincopan N, Stehling EG, Furlan JPR. Critical-priority resistant bacteria hidden in ship ballast water: A challenge for global epidemiological surveillance. New Microbes New Infect. 2024;58:101236.
Seppala LJ, van der Velde N. How to tackle the global challenge of falls? Age Ageing. 2022;51(11).
Shadrova A, Linscheid P, Lukassek J, Lüdeling A, Schneider S. A Challenge for Contrastive L1/L2 Corpus Studies: Large Inter- and Intra-Individual Variation Across Morphological, but Not Global Syntactic Categories in Task-Based Corpus Data of a Homogeneous L1 German Group. Front Psychol. 2021;12:716485.
Sheikh A, Dhingra-Kumar N, Kelley E, Kieny MP, Donaldson LJ. The third global patient safety challenge: tackling medication-related harm. Bull World Health Organ. 2017;95(8):546-a.
Siahaan S, Herman MJ, Fitri N. Antimicrobial Resistance Situation in Indonesia: A Challenge of Multisector and Global Coordination. J Trop Med. 2022;2022:2783300.
Silva HP. The historic success of vaccination and the global challenge posed by inaccurate knowledge in social networks. Patient Educ Couns. 2021;104(1):213-4.
Singh B, Bhat A, Ravi K. Antibiotics Misuse and Antimicrobial Resistance Development in Agriculture: A Global Challenge. Environ Health (Wash). 2024;2(9):618-22.
Sleet DA. The Global Challenge of Child Injury Prevention. Int J Environ Res Public Health. 2018;15(9).
Smith BH, Raja SN. NeuPSIG: investing in solutions to the growing global challenge of neuropathic pain. Br J Anaesth. 2017;119(4):705-8.
Søgaard Jørgensen P, Jansen REV, Avila Ortega DI, Wang-Erlandsson L, Donges JF, Österblom H, et al. Evolution of the polycrisis: Anthropocene traps that challenge global sustainability. Philos Trans R Soc Lond B Biol Sci. 2024;379(1893):20220261.
Sousa Pinto G, Hung M, Okoya F, Uzman N. FIP's response to the COVID-19 pandemic: Global pharmacy rises to the challenge. Res Social Adm Pharm. 2021;17(1):1929-33.
Stone J, Barker SF, Gasevic D, Freak-Poli R. Participation in the Global Corporate Challenge(®), a Four-Month Workplace Pedometer Program, Reduces Psychological Distress. Int J Environ Res Public Health. 2023;20(5).
Subakumar K, Franklin BD, Garfield S. Analysis of the third WHO Global Safety Challenge 'Medication Without Harm' patient-facing materials: exploratory descriptive study. Eur J Hosp Pharm. 2021;28(Suppl 2):e109-e14.
Süle A. Antimicrobial resistance-a global challenge that deserves more attention! Eur J Hosp Pharm. 2022;29(2):65.
Titley MA, Butchart SHM, Jones VR, Whittingham MJ, Willis SG. Global inequities and political borders challenge nature conservation under climate change. Proc Natl Acad Sci U S A. 2021;118(7).
Torra J, Osuna MD, Merotto A, Vila-Aiub M. Editorial: Multiple Herbicide-Resistant Weeds and Non-target Site Resistance Mechanisms: A Global Challenge for Food Production. Front Plant Sci. 2021;12:763212.
Voicu MN, Ahmet AM, Turcu-Stiolica M, Turcu-Stiolica A, Barbulescu AL, Popescu F. Antibiotic Resistance, Still a Global Challenge. Curr Health Sci J. 2021;47(2):284-9.
Vuorio A, Kovanen PT, Santos RD, Raal F. Prevention of Cardiovascular Burden in COVID-19 Patients Suffering from Familial Hypercholesterolemia: A Global Challenge. Cardiol Ther. 2022;11(1):1-7.
Wang Y, Yin H, An L. An Upcoming Global Challenge: Efficient Recycling for End-of-Life Lithium-Ion Batteries. Glob Chall. 2022;6(12):2200184.
Warpeha KM, Chen SH, Mullié C. Editorial: Emerging Infectious and Vector-Borne Diseases: A Global Challenge, Volume II. Front Public Health. 2022;10:942950.
Warpeha KM, Munster V, Mullié C, Chen SH. Editorial: Emerging Infectious and Vector-Borne Diseases: A Global Challenge. Front Public Health. 2020;8:214.
Weatherup C, Azam S. A global challenge and a legal requirement: new findings can help the Welsh response and put sustainable development into practice. Eur J Public Health. 2020;30(Suppl_1):i41-i2.
Weaver SC. Prediction and prevention of urban arbovirus epidemics: A challenge for the global virology community. Antiviral Res. 2018;156:80-4.
Wu B. Social isolation and loneliness among older adults in the context of COVID-19: a global challenge. Glob Health Res Policy. 2020;5:27.
Yang F, Zhang J, Liu Q, Liu H, Zhou Y, Yang W, et al. Improvement and Re-Evolution of Tetraploid Wheat for Global Environmental Challenge and Diversity Consumption Demand. Int J Mol Sci. 2022;23(4).
Young MF, Luo H, Suchdev PS. The challenge of defining the global burden of iron deficiency anaemia. Lancet Haematol. 2023;10(9):e702-e4.
Zhang H, Jiang X. Insights into global surgery: The biggest challenge faced by Chinese surgery. Surg Open Sci. 2023;15:43.
Zhang TY, Zhong B. Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19. Med Drug Discov. 2020;5:100036.
Zou J, Yang H. The Aging Spine: China Facing Up to the Global Challenge. Int J Spine Surg. 2022;16(5):861-2.
Correction: A Global View of Transcriptome Dynamics during Sporisorium scitamineum Challenge in Sugarcane by RNA-seq. PLoS One. 2015;10(2):e0118445.
Adachi K, Nielsen-Saines K, Klausner JD. Chlamydia trachomatis Infection in Pregnancy: The Global Challenge of Preventing Adverse Pregnancy and Infant Outcomes in Sub-Saharan Africa and Asia. Biomed Res Int. 2016;2016:9315757.
Agarwal AK, Ginisha G, Preeti G, Dwivedi S, Swamai P. The association between diabetes and tuberculosis may be the next challenge for global tuberculosis control worldwide. Indian J Endocrinol Metab. 2016;20(5):732-3.
Ali SF, Onaivi ES, Dodd PR, Cadet JL, Schenk S, Kuhar MJ, et al. Understanding the Global Problem of Drug Addiction is a Challenge for IDARS Scientists. Curr Neuropharmacol. 2011;9(1):2-7.
Anderson CC. Placing regulatory T cells into global theories of immunity: an analysis of Cohn's challenge to integrity (Dembic). Scand J Immunol. 2009;69(4):306-9.
Ausweger C, Burgschwaiger E, Kugler A, Schmidbauer R, Steinek I, Todorov Y, et al. Economic concerns about global healthcare in lung, head and neck cancer: meeting the economic challenge of predictive, preventive and personalized medicine. Epma j. 2010;1(4):627-31.
Basu S, Høilund-Carlsen PF, Alavi A. Assessing global cardiovascular molecular calcification with 18F-fluoride PET/CT: will this become a clinical reality and a challenge to CT calcification scoring? Eur J Nucl Med Mol Imaging. 2012;39(4):660-4.
Becker S. A historic and scientific review of breast cancer: The next global healthcare challenge. Int J Gynaecol Obstet. 2015;131 Suppl 1:S36-9.
Bedard N, Pierce M, El-Nagger A, Anandasabapathy S, Gillenwater A, Richards-Kortum R. Emerging roles for multimodal optical imaging in early cancer detection: a global challenge. Technol Cancer Res Treat. 2010;9(2):211-7.
Bergman H, Karunananthan S, Robledo LM, Brodsky J, Chan P, Cheung M, et al. Understanding and meeting the needs of the older population: a global challenge. Can Geriatr J. 2013;16(2):61-5.
Bothamley G, Lipman M, Kon OM. Cavitating pulmonary tuberculosis: a global challenge. Clin Med (Lond). 2012;12(3):299.
Boutros PC, Ewing AD, Ellrott K, Norman TC, Dang KK, Hu Y, et al. Global optimization of somatic variant identification in cancer genomes with a global community challenge. Nat Genet. 2014;46(4):318-9.
Burton R, Bell R. The global challenge of reducing breast cancer mortality. Oncologist. 2013;18 Suppl:3-5.
Burton R, Bell R. The global challenge of reducing breast cancer mortality. Oncologist. 2013;18(11):1200-2.
Butler CC. Antibiotics: Responding to a Global Challenge. Antibiotics (Basel). 2012;1(1):14-6.
Dagogo-Jack S. 2015 Presidential Address: 75 Years of Battling Diabetes--Our Global Challenge. Diabetes Care. 2016;39(1):3-9.
Damiano D, Forssberg H. We are the world: meeting the global challenge of childhood disability. Dev Med Child Neurol. 2016;58(7):649.
Devaux CA. Emerging and re-emerging viruses: A global challenge illustrated by Chikungunya virus outbreaks. World J Virol. 2012;1(1):11-22.
Eggleston K, Zhang R, Zeckhauser RJ. The global challenge of antimicrobial resistance: insights from economic analysis. Int J Environ Res Public Health. 2010;7(8):3141-9.
Gallardo MC, Reoyo AT, Fernández-Pinero J, Iglesias I, Muñoz MJ, Arias ML. African swine fever: a global view of the current challenge. Porcine Health Manag. 2015;1:21.
Garon JR, Cochi SL, Orenstein WA. The Challenge of Global Poliomyelitis Eradication. Infect Dis Clin North Am. 2015;29(4):651-65.
Gozal D, Mason KP. Pediatric sedation: a global challenge. Int J Pediatr. 2010;2010:701257.
Gray A, Manasse HR, Jr. Shortages of medicines: a complex global challenge. Bull World Health Organ. 2012;90(3):158-a.
Greenbaum D. Grand challenge: ELSI in a changing global environment. Front Genet. 2013;4:158.
Hanna EG, Tait PW. Limitations to Thermoregulation and Acclimatization Challenge Human Adaptation to Global Warming. Int J Environ Res Public Health. 2015;12(7):8034-74.
Holden B, Sankaridurg P, Smith E, Aller T, Jong M, He M. Myopia, an underrated global challenge to vision: where the current data takes us on myopia control. Eye (Lond). 2014;28(2):142-6.
Horwood C. The challenge of improving neonatal mortality in India, key to global achievement of MDG 4. Indian Pediatr. 2011;48(12):941-2.
Igarashi T. The challenge to integrate academic research in Japan into global R&D in pharmaceutical companies. Drug Metab Pharmacokinet. 2011;26(5):441.
Iserson KV. Tackling the global challenge: humanitarian catastrophes. West J Emerg Med. 2014;15(2):231-40.
Khan SR, Baghdasarian A, Fahlman RP, Siraki AG. Global protein expression dataset acquired during isoniazid-induced cytoprotection against H2O2 challenge in HL-60 cells. Data Brief. 2016;6:823-8.
Kourtis AP, Bulterys M, Hu DJ, Jamieson DJ. HIV-HBV coinfection--a global challenge. N Engl J Med. 2012;366(19):1749-52.
Kuchenbecker R, Grangeiro A, Veras MA. Global targets, local epidemics: the ultimate challenge for AIDS in Brazil? Rev Bras Epidemiol. 2015;18 Suppl 1:5-6.
Kumar RK. Training pediatric heart surgeons for the future: A global challenge. Ann Pediatr Cardiol. 2015;8(2):99-102.
Langley JM, Naus M. Immunization: a global challenge for the 21st Century. Expert Rev Vaccines. 2011;10(4):429-31.
Leone L, McCourt ME. The effect of acute ethanol challenge on global visuospatial attention: exaggeration of leftward bias in line bisection. Laterality. 2010;15(3):327-42.
Liang HJ, Lin Y, Zhang C, Ungvari GS, Tang WK. Drug Addiction: A Global Challenge. East Asian Arch Psychiatry. 2016;26(2):43-4.
Lunze K, Bloom DE, Jamison DT, Hamer DH. The global burden of neonatal hypothermia: systematic review of a major challenge for newborn survival. BMC Med. 2013;11:24.
Madhwani KP. Safe development of nanotechnology: A global challenge. Indian J Occup Environ Med. 2013;17(3):87-8.
Magee DA, Taraktsoglou M, Killick KE, Nalpas NC, Browne JA, Park SD, et al. Global gene expression and systems biology analysis of bovine monocyte-derived macrophages in response to in vitro challenge with Mycobacterium bovis. PLoS One. 2012;7(2):e32034.
Maksaereekul S, Dubie RA, Shen X, Kieu H, Dean GA, Sparger EE. Vaccination with vif-deleted feline immunodeficiency virus provirus, GM-CSF, and TNF-alpha plasmids preserves global CD4 T lymphocyte function after challenge with FIV. Vaccine. 2009;27(28):3754-65.
Mathers TC, Hammond RL, Jenner RA, Hänfling B, Gómez A. Multiple global radiations in tadpole shrimps challenge the concept of 'living fossils'. PeerJ. 2013;1:e62.
Mavrommatis B, Offord V, Patterson R, Watson M, Kanellos T, Steinbach F, et al. Global gene expression profiling of myeloid immune cell subsets in response to in vitro challenge with porcine circovirus 2b. PLoS One. 2014;9(3):e91081.
Mikesch JH, Gronemeyer H, So CW. Discovery of novel transcriptional and epigenetic targets in APL by global ChIP analyses: Emerging opportunity and challenge. Cancer Cell. 2010;17(2):112-4.
Mock C, Margie P, Hyder AA, Butchart A, Krug E. Child injuries and violence: responding to a global challenge. Bull World Health Organ. 2009;87(5):326.
Montine TJ, Larson EB. Late-life dementias: does this unyielding global challenge require a broader view? Jama. 2009;302(23):2593-4.
Mouzaki M, Allard J. Non-alcoholic steatohepatitis: the therapeutic challenge of a global epidemic. Ann Gastroenterol. 2012;25(3):207-17.
National Research Council Committee on Comparative National Innovation Policies: Best Practice for the 21st C. The National Academies Collection: Reports funded by National Institutes of Health. In: Wessner CW, Wolff AW, editors. Rising to the Challenge: US Innovation Policy for the Global Economy. Washington (DC): National Academies Press (US)
Copyright © 2012, National Academy of Sciences.; 2012.
Nevill PG, Tomlinson S, Elliott CP, Espeland EK, Dixon KW, Merritt DJ. Seed production areas for the global restoration challenge. Ecol Evol. 2016;6(20):7490-7.
Nishi R, Castañeda E, Davis GW, Fenton AA, Hofmann HA, King J, et al. The Global Challenge in Neuroscience Education and Training: The MBL Perspective. Neuron. 2016;92(3):632-6.
Ntizimira CR, Nkurikiyimfura JL, Mukeshimana O, Ngizwenayo S, Mukasahaha D, Clancy C. Palliative care in Africa: a global challenge. Ecancermedicalscience. 2014;8:493.
Onyango AW. Promoting healthy growth and preventing childhood stunting: a global challenge. Matern Child Nutr. 2013;9 Suppl 2(Suppl 2):1-5.
Papanas N, Maltezos E. The diabetic foot: a global threat and a huge challenge for Greece. Hippokratia. 2009;13(4):199-204.
Pezzola A, Sweet CM. Global pharmaceutical regulation: the challenge of integration for developing states. Global Health. 2016;12(1):85.
Que Y, Su Y, Guo J, Wu Q, Xu L. A global view of transcriptome dynamics during Sporisorium scitamineum challenge in sugarcane by RNA-Seq. PLoS One. 2014;9(8):e106476.
Quissell K, Walt G. The challenge of sustaining effectiveness over time: the case of the global network to stop tuberculosis. Health Policy Plan. 2016;31 Suppl 1(Suppl 1):i17-32.
Qureshi SR, Abdelaal AM, Janjua ZA, Alasmari HA, Obad AS, Alamodi A, et al. Irritable Bowel Syndrome: A Global Challenge Among Medical Students. Cureus. 2016;8(8):e721.
Ram S. A Bibliometric Assessment of Global Ice Bucket Challenge (Amyotrophic Lateral Sclerosis) Research. Ann Neurosci. 2016;23(4):209-17.
Rhodes SD, Kelley C, Simán F, Cashman R, Alonzo J, McGuire J, et al. Using community-based participatory research (CBPR) to develop a community-level HIV prevention intervention for Latinas: a local response to a global challenge. Womens Health Issues. 2012;22(3):e293-301.
Rodgers ZB, Jain V, Englund EK, Langham MC, Wehrli FW. High temporal resolution MRI quantification of global cerebral metabolic rate of oxygen consumption in response to apneic challenge. J Cereb Blood Flow Metab. 2013;33(10):1514-22.
Rodriguez-Galindo C, Friedrich P, Alcasabas P, Antillon F, Banavali S, Castillo L, et al. Toward the Cure of All Children With Cancer Through Collaborative Efforts: Pediatric Oncology As a Global Challenge. J Clin Oncol. 2015;33(27):3065-73.
Rosen JM, Kun L, Mosher RE, Grigg E, Merrell RC, Macedonia C, et al. Cybercare 2.0: meeting the challenge of the global burden of disease in 2030. Health Technol (Berl). 2016;6(1):35-51.
Rossor M, Knapp M. Can we model a cognitive footprint of interventions and policies to help to meet the global challenge of dementia? Lancet. 2015;386(9997):1008-10.
Ryder S, Pett S, Cooke GS. Genotype 4 and the global challenge of hepatitis C treatment. Lancet Gastroenterol Hepatol. 2016;1(1):3-4.
Saeed W. Cavitating pulmonary tuberculosis: a global challenge. Clin Med (Lond). 2012;12(1):40-1.
Satlin MJ, Jenkins SG, Walsh TJ. The global challenge of carbapenem-resistant Enterobacteriaceae in transplant recipients and patients with hematologic malignancies. Clin Infect Dis. 2014;58(9):1274-83.
Sattari SZ, Bouwman AF, Martinez Rodríguez R, Beusen AH, van Ittersum MK. Negative global phosphorus budgets challenge sustainable intensification of grasslands. Nat Commun. 2016;7:10696.
Schatlo B, Gläsker S, Zauner A, Thompson BG, Oldfield EH, Pluta RM. Continuous neuromonitoring using transcranial Doppler reflects blood flow during carbon dioxide challenge in primates with global cerebral ischemia. Neurosurgery. 2009;64(6):1148-54; discussion 54.
Scior K, Hamid A, Hastings R, Werner S, Belton C, Laniyan A, et al. Consigned to the margins: a call for global action to challenge intellectual disability stigma. Lancet Glob Health. 2016;4(5):e294-5.
Stamm LV. Global challenge of antibiotic-resistant Treponema pallidum. Antimicrob Agents Chemother. 2010;54(2):583-9.
The L. MERS-CoV: a global challenge. Lancet. 2013;381(9882):1960.
Thomas DL. Global control of hepatitis C: where challenge meets opportunity. Nat Med. 2013;19(7):850-8.
Verma R, Khanna P. Development of Toxoplasma gondii vaccine: A global challenge. Hum Vaccin Immunother. 2013;9(2):291-3.
Wada K, Sugiura Y, Akashi H, Nakasa T. Emergency government response team for global infectious disease outbreaks-a Japanese challenge. Trop Med Health. 2016;44:35.
Rigi A, Harati K, Abbaspour M, Fattahpour SF, Hosseini P, Fard AM, et al. AI and Deep Learning in Understanding the Etiology and Pathogenesis of Autoimmune Diseases. Kindle. 2024;4(1):1-182.
Nemati P, Khalaji A, Rajabloo Y, Kazemi MH, Nouri S, Mohebbi S, et al. AI and Deep Learning in Understanding the Etiology and Pathogenesis of Cancers. Kindle. 2024;4(1):1-173.
Khorsand M-S, Heidari S, Darbani R, Tosi YEK, Pourasad MH, Rajabloo Y, et al. AI Chatbots and Telemedicine in Cancer Care: Supporting Patients and Enhancing Communications. Kindle. 2024;4(1):1-205.
Karimian S, Taheri F, Farrokhi M, Farrokhi M, Bayat Z, Zadeh SAM, et al. Digital Health and Wearable Technologies. Kindle. 2024;4(1):1-240.
Farrokhi M, Taheri F, Moeini A, Farrokhi M, Khouzani PJ, Ghadirzadeh E, et al. Artificial Intelligence for Drug Development, Personalized Prescriptions, and Adverse Event Prediction. Kindle. 2024;4(1):1-180.
Farrokhi M, Taheri F, Moeini A, Farrokhi M, Alireza MZS, Farahmandsadr M, et al. Artificial Intelligence for Remote Patient Monitoring: Advancements, Applications, and Challenges. Kindle. 2024;4(1):1-261.
Farrokhi M, Taheri F, Farrokhi M, Tosi YEK, Ghadirzadeh E, Bagheri M, et al. Nanomedicine: Technologies and Applications. Kindle. 2024;4(1):1-196.
Farrokhi M, Taheri F, Farrokhi M, Moeini A, Tooyserkani SH, Shahali A, et al. Anti-Aging Strategies to Prevent Diseases: Promoting Longevity and Optimal Health. Kindle. 2024;4(1):1-194.
Farrokhi M, Taheri F, Farrokhi M, Heydari Z, Darbani R, Salbi M, et al. Advancements and Innovations in Cancer Management: A Comprehensive Perspective. Kindle. 2024;4(1):1-161.
Farrokhi M, Taheri F, Farrokhi M, Emtiazi N, Talebi M, Akbari A, et al. Human and AI: Collaborative Medicine in the Age of Technology. Kindle. 2024;4(1):1-160.
Farrokhi M, Taheri F, Bayat Z, Damiri M, Farrokhi M, Ghadirzadeh E, et al. Role of Lifestyle Medicine in the Prevention and Treatment of Diseases. Kindle. 2024;4(1):1-219.
Farrokhi M, Taheri F, Adibnia E, Mehrtabar S, Rassaf Z, Tooyserkani SH, et al. The AI Diagnostician: Improving Medical Diagnosis with Artificial Intelligence. Kindle. 2024;4(1):1-219.
Farrokhi M, Khouzani SJ, Farrokhi M, Jalayeri H, Faranoush P, Babaei M, et al. Artificial Intelligence and Deep Learning for Screening and Risk Assessment of Cancers. Kindle. 2024;4(1):1-140.
Amiri H, Ghaneiyan M, Farjami P, Mehran H, Mohammadzadeh S, Ghaderi S, et al. AI-Enhanced Virtual Clinics and Telemedicine for Cancer Treatment. Kindle. 2024;4(1):1-207.
Rezaei M, Azarshab M. Research Hotspots and Global Mapping of Publications in the Role of Artificial Intelligence in Cancer: A Bibliometric Study. Journal of Reviews in Medical Sciences. 2024;4(1):1-10.
